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Tunis Med ; 78(8-9): 484-93, 2000.
Article in English | MEDLINE | ID: mdl-11190724

ABSTRACT

We report 65 cases of MALT gastric lymphomas. HP was looked for with Giemsa and Whartin Starry stains. Immunohistochemistry was done with PAP method. Anti-HP treatment was used in 9 cases. 38 were of low grade of malignancy, 23 were high grade, 4 were high grade with a low grade component. The mean age was 51.5 years, the sex ratio 1.5. Epigastric pain was the most frequent feature (87.7% of cases). Endoscopically, low grade lymphomas presented as unique or multiple ulcerations (55.3% of cases) with antral localisation (52.6% of cases). 60% of our patients were stage IE, of which 61% had low grade lymphoma, 18% were at stage II2E, 10% at stage III and 10% at stage IV. From 23 operated patients, 29% had early lymphoma which was low grade malignant in 71.5% of cases, and 71% had lymphomas which were widely spread beyond the submucosa. HP was found in 63% of cases. Histologic regression of two early lymphomas of low grade malignancy was achieved after HP eradication.


Subject(s)
Helicobacter Infections/complications , Helicobacter pylori , Lymphoma, B-Cell, Marginal Zone/microbiology , Lymphoma, B-Cell, Marginal Zone/pathology , Stomach Neoplasms/microbiology , Stomach Neoplasms/pathology , Adult , Aged , Aged, 80 and over , Biopsy , Female , Gastrectomy , Gastroscopy , Helicobacter Infections/drug therapy , Humans , Immunohistochemistry/methods , Lymphoma, B-Cell, Marginal Zone/surgery , Male , Middle Aged , Neoplasm Staging , Prospective Studies , Retrospective Studies , Stomach Neoplasms/surgery
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