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Arch Mal Coeur Vaiss ; 95(7-8): 709-12, 2002.
Article in French | MEDLINE | ID: mdl-12365084

ABSTRACT

In the Bordeaux cohort of never treated, uncomplicated hypertensive patients with office BP > 140/90 on at least 2 occasions, we selected those with good quality 24 H ambulatory BP measurement and LVM measured with M mode echo before any antihypertensive treatment. In this group, we studied the relationships between LVM and average 24 h systolic BP in males and females in univariate and multivariate analysis, taking into account age, weight and height. The population studied included 531 patients whose main characteristics are summarized in the table. The slope of the relationship between LVM and 24 h SBP is significantly steeper in males than in females (1.73 vs 0.58, p < 0.01). In multivariate analysis, the variable showing the higher correlation to LVM is 24 h SBP in males, weight in females. For a similar increase in BP, males hypertensive show a higher increase in LVM than females.


Subject(s)
Hypertension/physiopathology , Hypertrophy, Left Ventricular/complications , Ventricular Function , Adult , Cohort Studies , Echocardiography , Female , Heart Ventricles/pathology , Humans , Hypertrophy, Left Ventricular/pathology , Male , Middle Aged , Regression Analysis , Sex Factors
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