Subject(s)
Dermatitis, Exfoliative/genetics , Dermatitis, Exfoliative/pathology , Hyperhidrosis/genetics , Hyperhidrosis/pathology , Mutation , Pigmentation Disorders/genetics , Pigmentation Disorders/pathology , Siblings , Transglutaminases/genetics , Administration, Cutaneous , Biomarkers/metabolism , Child , Child, Preschool , Dermatitis, Exfoliative/drug therapy , Education, Medical, Continuing , Emollients/administration & dosage , Emollients/therapeutic use , Female , Foot , Hand , Humans , Hyperhidrosis/drug therapy , Male , Pigmentation Disorders/drug therapy , Skin Diseases/congenitalSubject(s)
Alopecia/diagnosis , Alopecia/genetics , Codon, Nonsense , Hyperpigmentation/diagnosis , Hyperpigmentation/genetics , Nail Diseases/diagnosis , Nail Diseases/genetics , Skin Neoplasms/diagnosis , Skin Neoplasms/genetics , Adult , Alopecia/drug therapy , Etretinate/therapeutic use , Female , Humans , Hyperpigmentation/drug therapy , Keratolytic Agents/therapeutic use , Male , Nail Diseases/drug therapy , Siblings , Skin Neoplasms/drug therapy , Treatment OutcomeABSTRACT
A prospective study of syphilis cases over a period of 2 years (January 2008 to September 2009) was carried out in the Department of Dermatology of the Hassan II University Hospital Center in Fes, Morocco. A total of 57 cases were identified. The M/F sex ratio was 0.89. Mean patient age was 40.5 years (range, 22-80). Risk factors included unprotected sex in 96.5% of cases and multiple partners in 42.1%. Nine patients had a history of sexually transmitted infection. No patient had received blood transfusion. Clinical picture was late latent syphilis in 70.2% of cases (n = 41). Only one case was associated with human immunodeficiency virus. The mainstay treatment was intramuscular benzathine benzylpenicillin. Outcome was favorable in 48 cases.
