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1.
Clin Exp Dermatol ; 47(8): 1583-1584, 2022 Aug.
Article in English | MEDLINE | ID: mdl-35436008

ABSTRACT

We report a patient with carbamazepine-induced drug reaction with eosinophilia and systemic symptoms (DRESS), who developed painful dysphagia in the follow-up period. Gastrointestinal, including oesophageal, complications are rarely reported following DRESS, and we wish to highlight this possibly under-reported phenomenon.


Subject(s)
Drug Hypersensitivity Syndrome , Eosinophilia , Anticonvulsants/adverse effects , Carbamazepine/adverse effects , Drug Hypersensitivity Syndrome/diagnosis , Eosinophilia/drug therapy , Esophagus , Humans
2.
Clin Exp Gastroenterol ; 14: 477-492, 2021.
Article in English | MEDLINE | ID: mdl-34992406

ABSTRACT

Delayed post-polypectomy bleeding (DPPB) is a potentially severe complication of therapeutic colonoscopy which can result in hospital readmission and re-intervention. Over the last decade, rates of DPPB reported in the literature have fallen from over 2% to 0.3-1.2%, largely due to improvements in resection technique, a shift towards cold snare polypectomy, better training, adherence to guidelines on periprocedural antithrombotic management, and the use of antithrombotics with more favourable bleeding profiles. However, as the complexity of polypectomy undertaken worldwide increases, so does the importance of identifying patients at increased risk of DPPB. Risk factors can be categorised according to patient, polyp and personnel related factors, and their integration together to provide an individualised risk score is an evolving field. Strategies to reduce DPPB include safe practices relevant to all patients undergoing colonoscopy, as well as specific considerations for patients identified to be high risk. This narrative review sets out an evidence-based summary of factors that contribute to the risk of DPPB before discussing pragmatic interventions to mitigate their risk and improve patient safety.

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