ABSTRACT
The objective of this paper was to evaluate effect of laser's biostimulation on the process of healing of crural ulcerations. Three comparative groups of patients, A, B and C, were made at random from the patients with venous crural ulcerations. The group A consisted of 17, the group B 15, the group C 17 patients. The patients in all comparative groups were treated pharmacologically and got compress therapy. Ulcerations at patients in group A were additionally irradiated by light of biostimulation's laser (810 nm) in this way that every time ulcerations got dose of energy 4 J/cm2. The patient's in-group B additionally got blind trial (with placebo in the form of quasi-laserotherapy). The evaluated factors were to estimate how laser's biostimulation causes any changes of the size of the ulcers and of the volume of tissue defect. The speed of changes of size and volume of tissue defect per week was calculated. After the treatment there was statistically significant decrease of size of ulcers in all comparative groups while there was no statistically significant difference between the groups observed. After the treatment there was statistically significant decrease of volume of ulcers only in groups A and C but there was no statistically significant difference between the groups observed.
Subject(s)
Leg/physiopathology , Low-Level Light Therapy/methods , Varicose Ulcer/radiotherapy , Wound Healing , Adult , Aged , Aged, 80 and over , Dose-Response Relationship, Radiation , Female , Humans , Leg/pathology , Male , Middle Aged , Single-Blind Method , Time Factors , Treatment OutcomeABSTRACT
The results of leg ulcers treatment in two comparative groups, A and B, are presented in the article. In the group A 22 patients with leg ulcers were treated with the use of high voltage electrical stimulation. In the group B 20 patients with leg ulcers were treated actively with the use of traditional methods. The average time of treating patients subjected to electrical stimulation was 7 weeks and in the control group the average time of treatment was 6 weeks. The healing progress was estimated on the basis of rate of wounds surfaces and volumes changes per week and their proportional changes. In the group A the average rate of ulcer surface decreasing was 1.4 cm2 per week and the average volume diminishing in this group was 1.0 cm2 per week. These indicators in the group B were respectively 1.0 cm2 and 0.6 cm3. In the group A wound surface decreased by 73.4% during the treatment and wound volume by 91.3%. In the group B these indicators were respectively 46.9% and 67.6%. After the treatment all indicators estimating the progress of wound healing in the groups A and B proved the statistically significant increases. The proportional indicators of wounds surfaces and volumes were significantly higher in the group A than in the group B.
Subject(s)
Ulcer/therapy , Wound Healing , Adult , Aged , Aged, 80 and over , Electric Stimulation/methods , Female , Humans , Leg , Male , Middle Aged , Treatment OutcomeABSTRACT
In this study the serum calcitonin concentrations were assessed in patients with Psoriasis vulgaris. The results were compared with healthy volunteers. The serum calcitonin levels of psoriatic patients was significantly increased than in healthy volunteers.
Subject(s)
Calcium/blood , Psoriasis/blood , Adult , Humans , Male , Middle AgedABSTRACT
The concentrations of Na+, K+, Li+ have been assayed in the epidermis samples from 58 cadavers and 20 healthy individuals. The samples have been taken from the heels, and assayed with 2 flame photometers (Corning 480), using standard solutions supplied by the manufacturer. A concentration of Na+ and K+ in men exceeded the levels of these ions in women by two-fold. A level of Li+ is the same in both sexes and amounts to 2.8 mEq/kg. The Na+:K+ ratio in the epidermis of women and men is about 4:1. In the samples collected from cadavers, the difference in Na+ and K+ levels has been lower but Li+ level has been higher, amounting to 4.3 mEq/kg.
Subject(s)
Ion Channels/metabolism , Lithium/metabolism , Postmortem Changes , Potassium/metabolism , Sodium Chloride/metabolism , Adult , Aged , Female , Humans , Male , Middle AgedABSTRACT
A rare case of porphyria cutanea tarda (PCT) in an 11-year-old boy is presented. The clinical manifestations were typical. Results of porphyrin analyses of urine and serum with a fluorescence emission maximum around 398 nm revealed a pattern consistent with PCT.
Subject(s)
Porphyria Cutanea Tarda/diagnosis , Animals , Child , Giardia lamblia/isolation & purification , Humans , Male , Porphyria Cutanea Tarda/parasitologyABSTRACT
In 51 patients, 29 female and 22 male of average 61 years old, 94 lesions were treated with Nd: YAG laser; 70 basal-cell carcinomas, 9 superficial basal-cell carcinomas, 12 actinic keratosis and 3 cutaneous horns. Size of changes varied from 7 to 24 mm. Quantity of energy used in laser-therapy was dependent on diagnosis, focus size, location and amounted from 50 to 240 J/cm2. Authors are of the opinion that Nd:YAG laser-therapy is a very good method for treatment of skin tumors. Moreover, the advantage of this method is its possibility of a single procedure in the conditions of outpatients clinic.
Subject(s)
Carcinoma, Basal Cell/surgery , Laser Therapy/methods , Precancerous Conditions/surgery , Skin Neoplasms/surgery , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle AgedABSTRACT
Dermatological examination and patch tests were done in 114 manufacturers of tires, 78 women and 36 men, mean age 29 years, working in Stomil Plant. Patch tests included 15 substances in panels Standard I and II (excluding rubber components). The study demonstrated hypersensitivity to nickel and formalin (4.3% each), chromium and cobalt (3.5% each), and turpentine (2.6%), while hypersensitivity to other allergens was observed sporadically. A comparative analysis of the results of patch tests with antigens "Standard I and II" in confectioners and healthy and allergic persons showed that the per cent of positive tests in rubber industry workers was higher than in healthy subjects, and much lower than in patients with contact dermatitis.