Subject(s)
Acetabulum/chemistry , Durapatite/chemistry , Polyethylene/chemistry , Prostheses and Implants , Animals , Biocompatible Materials/adverse effects , Durapatite/adverse effects , Erythrocyte Count , Hip Joint/surgery , Humans , Knee Joint/surgery , Leukocyte Count , Mutagenesis , Polyethylene/adverse effects , Prostheses and Implants/adverse effects , RatsSubject(s)
Boron Compounds/chemistry , Materials Testing , Polyethylene/chemistry , Polymers/chemistry , Radiation Protection , Sulfones/chemistry , Tungsten/chemistry , Animals , Boron Compounds/pharmacology , Humans , Mice , Polyethylene/pharmacology , Polymers/pharmacology , Sulfones/pharmacology , Tungsten/pharmacologyABSTRACT
The results of analysis of elemental composition of human bone tissue by the method of laser mass spectrometry are published for the first time. This method makes it possible to detect about 20 elements of bone tissue at once. Quantitative analysis of 1 microgram/gram of an element contained in bone tissue is sufficient to diagnose of human medico-biological characteristics by this method.
Subject(s)
Bone and Bones/chemistry , Forensic Anthropology/methods , Forensic Pathology/methods , Lasers , Mass Spectrometry/methods , Adult , Aged , Aged, 80 and over , Bone and Bones/pathology , Cadaver , Elements , Female , Humans , Male , Middle Aged , RussiaABSTRACT
The results of an experimental study dealing with the elementary composition of bone tissue by using the method of laser mass spectrometry are described in the paper. The method ensures the quantification of concentration values of all elements from the Mendeleev periodic table that can be made within an extensive dynamic range, which makes it promising in the forensic medical identification.
Subject(s)
Bone and Bones/chemistry , Forensic Anthropology/methods , Lasers , Mass Spectrometry/methods , Elements , HumansABSTRACT
The paper deals with laser mass spectrometric determination of elements from the materials to be implanted into the animal organs by using the sieve endoprostheses made of titanium nickelide.
Subject(s)
Implants, Experimental , Trace Elements/analysis , Animals , Intestines/chemistry , Kidney/chemistry , Liver/chemistry , Lung/chemistry , Male , Nickel , Rats , Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization , TitaniumABSTRACT
Laser mass spectrometric analysis of a biomedical sample was made on exposure to laser radiation at lambda 2 = 532 nm. The parameters of laser radiation and mass spectra were comparatively analyzed by using the basic and second harmonics of aluminum-yttrium-garnet-based laser. The sensitivity of laser mass spectrometry of biomedical samples is increased.
Subject(s)
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization , Animals , Lasers , Liver/chemistry , Models, Theoretical , Rats , Sensitivity and SpecificityABSTRACT
Several modifications of copper amalgams were examined. The findings evidence that of the amalgam constituents only copper passes into saliva, nutrient media, and animal body tissues and accumulates there. The findings of sanitary chemical and toxicologic studies helped select a hygienically optimal copper amalgam sample exerting no detrimental effects on the body.
Subject(s)
Copper/chemistry , Dental Amalgam/chemistry , Animals , Copper/analysis , Copper/toxicity , Dental Amalgam/analysis , Dental Amalgam/toxicity , Dental Restoration, Permanent , Drug Stability , Male , Rats , Tablets , Time FactorsABSTRACT
Quantitative analyses of the whole microcomposition at a time without using the standards are shown to be realizable by the laser mass-spectrometry carried out on the domestic device EMAL-2. The techniques of sample preparation are simple and may be applied to analyze the wide range of medical and biological specimens. From the obtained results it is obvious that the mass-spectrometric method is useful in microanalyzing element compositions of medical and biological specimens.
