ABSTRACT
Gestational trophoblastic disease occurs rarely in postmenopausal women. We report the case of a 51 year-old postmenopausal woman with an invasive complete mole. Invasive mole should be distinguished from choriocarcinoma, by a thorough sampling showing infiltrative molar villi associated with a prominent trophoblastic proliferation. Gestational trophoblastic diseases in postmenopausal women can represent malignant changes of trophoblastic remnants of a prior pregnancy after a period of latency or correspond to a possible current pregnancy as demonstrated by an ovarian corpus luteum of pregnancy in our patient. The unusual finding in our case is that the gestational trophoblastic disease follows a pregnancy occurring after a biologically confirmed menopause.
Subject(s)
Hydatidiform Mole, Invasive/pathology , Uterine Neoplasms/pathology , Female , Humans , Hydatidiform Mole, Invasive/surgery , Hysterectomy , Middle Aged , Neoplasm Invasiveness , Neoplasm Staging , Ovarian Neoplasms/pathology , Ovarian Neoplasms/surgery , Postmenopause , Pregnancy , Uterine Neoplasms/surgeryABSTRACT
Giant cell fibroblastoma (GCF) is a rare neoplasm occurring mostly in children. It has a tendency to recur locally after treatment. We report a new case noticed in an five year-old child who developed recurrence a first time three years later with the picture of GCF and at a second time with the picture of dermatofibrosarcoma protuberans 17 months later.