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1.
Ann Pathol ; 23(5): 443-6, 2003 Oct.
Article in French | MEDLINE | ID: mdl-14752389

ABSTRACT

Gestational trophoblastic disease occurs rarely in postmenopausal women. We report the case of a 51 year-old postmenopausal woman with an invasive complete mole. Invasive mole should be distinguished from choriocarcinoma, by a thorough sampling showing infiltrative molar villi associated with a prominent trophoblastic proliferation. Gestational trophoblastic diseases in postmenopausal women can represent malignant changes of trophoblastic remnants of a prior pregnancy after a period of latency or correspond to a possible current pregnancy as demonstrated by an ovarian corpus luteum of pregnancy in our patient. The unusual finding in our case is that the gestational trophoblastic disease follows a pregnancy occurring after a biologically confirmed menopause.


Subject(s)
Hydatidiform Mole, Invasive/pathology , Uterine Neoplasms/pathology , Female , Humans , Hydatidiform Mole, Invasive/surgery , Hysterectomy , Middle Aged , Neoplasm Invasiveness , Neoplasm Staging , Ovarian Neoplasms/pathology , Ovarian Neoplasms/surgery , Postmenopause , Pregnancy , Uterine Neoplasms/surgery
2.
Ann Pathol ; 22(6): 465-8, 2002 Dec.
Article in French | MEDLINE | ID: mdl-12594389

ABSTRACT

Giant cell fibroblastoma (GCF) is a rare neoplasm occurring mostly in children. It has a tendency to recur locally after treatment. We report a new case noticed in an five year-old child who developed recurrence a first time three years later with the picture of GCF and at a second time with the picture of dermatofibrosarcoma protuberans 17 months later.


Subject(s)
Dermatofibrosarcoma/pathology , Fibrosarcoma/pathology , Skin Neoplasms/pathology , Antigens, CD/analysis , Child , Child, Preschool , Humans , Immunohistochemistry , Male , Recurrence
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