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1.
J Int Med Res ; 36(1): 9-16, 2008.
Article in English | MEDLINE | ID: mdl-18230262

ABSTRACT

This study investigated the relationship between adult attention deficit hyperactivity disorder (ADHD) and trauma. Fifty-eight adults admitted to hospital with musculoskeletal trauma were evaluated using scales that determine the presence of ADHD in childhood and adulthood. Each patient was also interviewed by an adult psychiatrist and a child and adolescent psychiatrist. The control group consisted of 30 adult patients with complaints other than trauma who did not have a history of repetitive traumas. There were 36 (62.2%) cases of ADHD in the patient group compared with four (13.3%) in the control group; this difference was statistically significant. When the level of trauma was evaluated, ADHD was identified in 23 of the 26 (88.5%) patients with high energy traumas compared with 14 of the 32 (43.8%) patients with low energy traumas; this difference was also statistically significant. This study shows that patients with adult ADHD are more prone to injuries, particularly high energy traumas such as motor vehicle accidents. Patients who have repeated high energy traumas should be evaluated by a psychiatrist for ADHD.


Subject(s)
Attention Deficit Disorder with Hyperactivity/complications , Wounds and Injuries/complications , Adolescent , Aged , Attention Deficit Disorder with Hyperactivity/diagnosis , Comorbidity , Female , Humans , Male , Middle Aged , Musculoskeletal System/injuries , Musculoskeletal System/pathology , Turkey/epidemiology
2.
Arch Orthop Trauma Surg ; 121(1-2): 17-25, 2001.
Article in English | MEDLINE | ID: mdl-11195113

ABSTRACT

Since the definition of three-dimensional components of the scoliotic deformity, there have been important improvements in the surgical treatment of the problem. A derotation maneuver was proposed as a treatment option with CD instrumentation, but the reports of imbalance and decompensation with this system repopularized sublaminar wiring and translation as a corrective maneuver. Isola spinal instrumentation is one of the modern systems that utilizes vertebral translation instead of rod rotation. This study analyzes the results of 24 patients with idiopathic scoliosis who had been followed up for at least 2 years, and were surgically treated with titanium Isola Spinal Instrumentation in the Department of Orthopaedics and Traumatology, Ankara Social Security Hospital. Patients were grouped according to the King-Moe classification. Patients with type III, IV or V curves received only posterior instrumentation while this procedure followed anterior release and discectomy in the same session in patients with type I or II curves. A translation maneuver was utilized in the correction of scoliotic curves using the cantilever technique, either alone or supplemented by sublaminar wiring with Songer multifilament titanium cables. This study aimed to elucidate the effects of this technique in the frontal and sagittal plane curves and the trunk balance. The balance was analyzed clinically and radiologically by measurement of the lateral trunk shift (LT), shift of stable vertebra (SS), and shift of head (SH) in vertebral units (VU). The postoperative correction was significant in the frontal plane for all types of curves (p < 0.05). The postoperative correction was 80.9% +/- 9.5% in type III curves. Overall, the mean Cobb angle of the major curve value in the frontal plane was 66.9 degrees +/- 18.8 degrees, and it was corrected by 62.8% +/- 20.1%. The correction loss of Cobb angles in the frontal plane was 5.4 degrees +/- 5.5 degrees at the last follow-up visit. A normal physiologic thoracic contour (30 degrees - 50 degrees) was achieved in 83.3% of the patients and normal lumbar contour (40 degrees - 60 degrees) in 66.7% of the patients in the sagittal plane. The correction was found to be significant in all balance values (p < 0.05). The postoperative correction in LT values correlated with the correction of the Cobb angle values in the frontal plane. All patients had complete balance (SH: 0 VU and SS: 0 VU) or balanced curves (0 VU < SH, SS < 0.5 VU).Finally, the study concluded that the translation maneuver, especially when used with the cantilever technique, resulted in high correction rates in the frontal plane. Additionally, the technique was also successful in obtaining normal sagittal contours and correcting balance values.


Subject(s)
Scoliosis/surgery , Spinal Fusion/instrumentation , Spinal Fusion/methods , Adolescent , Biomechanical Phenomena , Bone Wires , Equipment Design , Female , Follow-Up Studies , Humans , Male , Postural Balance , Radiography , Range of Motion, Articular , Rotation , Scoliosis/classification , Scoliosis/diagnostic imaging , Scoliosis/etiology , Scoliosis/physiopathology , Spinal Fusion/adverse effects , Treatment Outcome
3.
Kobe J Med Sci ; 47(6): 231-53, 2001 Dec.
Article in English | MEDLINE | ID: mdl-11870334

ABSTRACT

As scoliotic curve is a rotational deformity, derotation maneuvre was used as the corrective factor, but recent studies demonstrated spinal imbalance and decompensation problems in patients treated with this method. This study evaluates 217 late onset idiopathic scoliosis patients surgically treated with third generation instrumentation (Texas Scotish Rite Hospital System - TSRH) from September 1991 to November 1996 with a minimum 2 years follow up. Preoperative and postoperative Cobb angles in the frontal plane and thoracic kyphosis and lumbar lordosis angles in the sagittal plane are measured. The balance was analyzed clinically and radiologically by measurement of the lateral trunk shift (LT), shift of head (SH) and shift of stable vertebra (SS) in vertebral unit (VU). At final follow - up correction loss, infection and other complications were documented. Mean age of the patients was 14.8 +/- 2.3 and mean follow up period 55.8 +/- 29.5 months. When all the patients were included, preoperative mean Cobb angles of major curves in the frontal plane was 59.1 +/- 20.7 degrees. Major curves that were corrected by 34.8 +/- 20.5 % in the bending radiograms were achieved by 58.9 +/- 19.5 % correction postoperatively. At the last control, 7.3 degrees +/- 6.4 degrees of correction loss was recorded in major curves in the frontal plane. Also postoperative kyphosis angle and lumbar lordosis angles were 31.4 degrees +/- 11.6 degrees and 30.6 degrees +/- 10.9 degrees respectively. Postoperatively, a statistically significant correction was obtained in LT, SH and SS values. None of the patients had complete balance (SH: 0 VU, SS: 0 VU) preoperatively. Only 39.2 % of the patients had clinically balanced curves (0 VU < SH < 0.5 VU and 0 VU < SS < 0.5 VU). Postoperatively, 47.9 % of the patients were found to be completely balanced, while 43.8 % had a balanced curve. Overall 91.7 % of the patients had a trunk balance after surgical intervention. The remaining 8.3 % imbalanced curve rate raised up to 16.6 % at final follow up, but the loss of correction rates in S S and SH values were found to be insignificant. The postoperative "imbalance" problem was mostly seen in Type II and Type IV curves. However, at final follow up, the imbalance problem due to overcorrection which became evident especially by "shift of head" to opposite side was seen in all types of curves. It is established that high correction rates can be obtained in scoliotic curves with third - generation instrumentation. No undue effects were observed in the uninstrumented lumbar curves. Thoracic sagittal contours of the hypokyphotic patients were improved. Use of this instrumentation system causes minimal imbalance problems and with proper preoperative planning high correction rates can be achieved.


Subject(s)
Orthopedic Fixation Devices , Postural Balance , Scoliosis/physiopathology , Scoliosis/surgery , Age of Onset , Female , Humans , Male , Middle Aged , Radiography, Thoracic , Scoliosis/diagnostic imaging , Scoliosis/epidemiology , Treatment Outcome
4.
Kobe J Med Sci ; 46(1-2): 39-68, 2000 Apr.
Article in English | MEDLINE | ID: mdl-11193503

ABSTRACT

Classic procedure in the treatment of vertebral tuberculosis is drainage of the abscess, curettage of the devitalized vertebra and application of antituberculous chemotherapy regimen. Posterior instrumentation results are encouraging in the prevention or treatment of late kyphosis; however, a second stage operation is needed. Recently, posterolateral or transpedicular drainage without anterior drainage or posterior instrumentation following anterior drainage in the same session is preferred to avoid kyphotic deformity. Seventy-six patients with spinal tuberculosis were operated in the 1st Department of Orthopaedics and Traumatology, Ankara Social Security Hospital, between January 1987 and January 1997. There were four children in our series. Average follow-up period was 36.1 +/- 14.5 months and the average age at the time of operation was 40.8 +/- 15.2 years. This study reports the surgical results of 45 patients with Pott's disease who had anterior radical debridement with anterior fusion and anterior instrumentation [14 patients with Z-plate and 31 patients with Cotrel-Dubousset-Hopf (CDH system)]. The results are compared with those of 8 patients who had posterolateral drainage and posterior fusion, 12 patients who had only anterior drainage and anterior strut grafting and, 11 patients who had posterior instrumentation following anterior radical debridement in the same session in terms of fusion rates, correction of kyphotic deformity, recurrence rate and clinical results. All patients had one year consecutive triple drug therapy. Preoperative 23.2 degrees +/- 12.5 degrees local kyphosis angle was lowered to 6.1 degrees +/- 6.9 degrees with a correction rate of 77.4 +/- 22.3%. When the other three groups which had been instrumented were compared, the correction rates in the local kyphosis angle values were not statistically different and the variation in loss of correction at the last follow-up was also statistically insignificant. The sagittal contour of the involved vertebra's region did not change in the uninstrumented group, while it did so in instrumented groups which had normal range values postoperatively. Overall, 27 patients had neurologic deficits preoperatively. Twenty of these (74.1%) had complete, and 5 (18.5%) had partial recovery with a combined 92.6% neurologic improvement. All the patients had a solid fusion mass at the last controls. Reactivation was not seen. Additionally, contrary to the common belief, anterior instrumentation which anterior autologous strut grafting following anterior radical debridement can be a good treatment option with low complication rate, high correction rate in acute local kyphosis, and high fusion rate.


Subject(s)
Orthopedic Procedures/methods , Spinal Fusion/instrumentation , Thoracic Vertebrae , Tuberculosis, Spinal/diagnosis , Tuberculosis, Spinal/surgery , Adolescent , Adult , Aged , Bone Transplantation/methods , Child , Debridement/methods , Female , Follow-Up Studies , Humans , Male , Middle Aged , Probability , Retrospective Studies , Spinal Fusion/methods , Statistics, Nonparametric , Treatment Outcome , Turkey
5.
Eur Spine J ; 9(6): 505-15, 2000 Dec.
Article in English | MEDLINE | ID: mdl-11189919

ABSTRACT

Anterior instrumentation for the correction of scoliotic curves has recently been gaining in popularity. The problems of high mortality and morbidity that were associated with the employment of anterior instrumentation in the first years it was used have now been overcome. Efforts are now being concentrated on increasing the correction rates in the frontal plane and decreasing the kyphotic effect in the sagittal plane. The anterior Cotrel-Dubousset-Hopf (CDH) system is a recently developed instrumentation that has been claimed to decrease the kyphotic effect through the use of double rods. This study aimed to investigate the impact of the anterior CDH system on idiopathic scoliotic curves in frontal and sagittal planes. To this end, 26 idiopathic scoliosis patients treated with the CDH system were followed for a mean period of 32.8 +/- 5.3 months. In the frontal plane, Cobb angles of major and secondary curves were measured, and postoperative and final correction rates determined. In the sagittal plane, sagittal contours of both the instrumented region and the thoracic and lumbar regions were measured, and their preoperative, postoperative and final control values were determined. In addition to clinical examination, lateral trunk shift (LT), shift of head (SH) and shift of stable vertebra (SS) were measured in vertebral units (VU), on the preoperative and postoperative radiographs in order to evaluate the effect of the system on trunk balance. It was established that in patients with single flexible thoracolumbar and lumbar curves and those with rigid thoracic curves, the correction rates obtained in the frontal plane were respectively 79.4 +/- 14.8%, 68.0 +/- 9.4% and 61.5 +/- 8.0%, with statistical significance. Their final corrections at the last control were 76.3 +/- 17.4%, 56.9 +/- 9.1% and 52.3 +/- 8.3%, respectively. Although the corrections in the lumbar rigid curves were relatively low, they were still statistically significant. Taking all the patients together, the mean preoperative Cobb angle of the major curves of 67.2 degrees +/- 20.2 degrees improved to a mean of 28.6 degrees +/- 21.0 degrees, which was a statistically significant difference (P < 0.05), giving a mean correction rate of 61.2 +/- 20.3%. The mean correction loss of major curves in the frontal plane in all patients was 6.0 degrees +/- 3.8 degrees and the mean final correction rate was 52.6 +/- 23.2%. In the sagittal plane, there was a favorable kyphotic effect on the thoracic region of patients with hypokyphosis and lordosis pattern, whilst in patients with kyphotic pattern, this effect was minimal. In patients with a single flexible lumbar curve, kyphotic effect was not observed except in two patients. In these two patients, it was thought that excessive compression force may have been used. As to the pa tients with rigid lumbar curve. there was a slight decrease in lumbar lordosis. No postoperative complaints were made about imbalance. and the mean overall correction in LT values was 60.1 +/- 21.7%. While preoperatively, the SH and SS values of all patients were over 0.5 VU, postoperatively, 12 patients (46.2%) were completely balanced (SH = 0 VU, SS = 0 VU) and 8 patients (30.8%) were balanced (0 VU < SH and SS < 0.5 VU). The remaining six patients, whose balance values were corrected with statistical significance but were still over 0.5 VU, were found to be the ones with rigid lumbar curves. Implant failure and systemic complications were not noted in the follow-up period. In view of these findings, it was determined that CDH instrumentation achieves significant correction rates in the frontal and sagittal planes, particularly in single flexible lumbar, thoracolumbar and thoracic rigid curves. It was found that the kyphotic effect was minimized with a double rod system. Significant clinical and radiological corrections were achieved in balance values, without any imbalance and decompensation problems.


Subject(s)
Internal Fixators/standards , Lumbar Vertebrae/surgery , Scoliosis/surgery , Spinal Fusion/instrumentation , Spinal Fusion/methods , Thoracic Vertebrae/surgery , Adolescent , Female , Humans , Internal Fixators/adverse effects , Lumbar Vertebrae/diagnostic imaging , Lumbar Vertebrae/pathology , Male , Postoperative Complications/etiology , Postural Balance/physiology , Radiography , Spinal Fusion/adverse effects , Thoracic Vertebrae/diagnostic imaging , Thoracic Vertebrae/pathology , Treatment Outcome
6.
Bull Hosp Jt Dis ; 58(2): 92-7, 1999.
Article in English | MEDLINE | ID: mdl-10509201

ABSTRACT

Anterior decompression enables direct access and good canal clearance of the injury level in thoracolumbar spinal fractures, and decompressing the neural elements is shown to be an important factor for neurologic improvement and pain relief in many cases. In this study, results with anterior decompression and Z-plate instrumentation in thoracolumbar spinal fractures are reviewed. Nineteen patients with old spinal fracture (average: 3 years) and neural compression, and 15 patients with fresh thoracolumbar fractures with neurologic deficit and/or major anterior spinal canal obstruction had anterior decompression and Z-plate instrumentation with anterior fusion. Stabilization was protected with thoracolumbar thermoplastic braces for six months. Preoperative kyphotic deformity averaged 20.9 degrees (range: 7 degrees to 64 degrees), while it was an average of 8.0 degrees (range: -12 degrees to 35 degrees) postoperatively. Medullary canal compromise was 41% an average (range: 13% to 67%) and postoperatively it had an average value of 6% (range: 0% to 18%). Patients were followed up an average of 30 months (range: 25 to 36 months). The unchanged positions of bone grafts and statistically insignificant loss of correction in the sagittal plane are accepted as evidence for bony fusion in all patients. Z-plate instrumentation provides stable fixation. Additionally, the technique can be performed easily and has the added benefit of being MRI-compatible.


Subject(s)
Bone Plates , Fracture Fixation, Internal/instrumentation , Lumbar Vertebrae/injuries , Spinal Fractures/surgery , Thoracic Vertebrae/injuries , Adolescent , Adult , Braces , Female , Follow-Up Studies , Fracture Fixation, Internal/methods , Humans , Male , Middle Aged , Pain Measurement , Range of Motion, Articular , Spinal Fractures/diagnosis , Spinal Fractures/rehabilitation , Treatment Outcome
7.
Bull Hosp Jt Dis ; 58(4): 184-7, 1999.
Article in English | MEDLINE | ID: mdl-10711365

ABSTRACT

Perioperative hemorrhage associated with major orthopaedic surgery can become life threatening. Homologous bank blood transfusion can replace the volume of blood lost but it has serious disadvantages such as the transmission of viral agents, it has an insufficient platelet count, and transfusion reactions are possible. Hypotensive anesthesia, predeposited autologous blood transfusion and intraoperative autotransfusion are used to reduce these disadvantages. This study evaluates the results of 700 patients who underwent major orthopaedic intervention in our clinic between June 1991 and April 1998. Ninety-nine patients had hip surgery while 601 patients had spinal surgery. The autotransfusion unit saved an average of 858.9 +/- 136.8 cc of blood and an average of 1.9 +/- 1.2 units of saved blood was transfused. None of these patients needed homologous blood transfusion. One hundred patients who had spinal surgery during the same period were used as a control group. The control group required an average of 3.2 +/- 2.1 units of bank blood. Preoperative and postoperative hematocrit values revealed a statistically significant difference between the autotransfusion group and the homologous transfusion group (p < 0.05). The results of this study suggest that intraoperative autotransfusion prevents the decrease in hematocrit values while reducing the need for bank blood transfusion and hence avoiding the risk of transmission of viral infections.


Subject(s)
Blood Transfusion, Autologous , Orthopedics , Adult , Aged , Blood Loss, Surgical , Blood Transfusion/statistics & numerical data , Female , Hematocrit , Humans , Intraoperative Period , Male , Middle Aged , Risk Factors , Transfusion Reaction
8.
Eur Spine J ; 5(6): 380-6, 1996.
Article in English | MEDLINE | ID: mdl-8988380

ABSTRACT

The basic principles of current idiopathic scoliosis treatment are three-dimensional correction and rigid fixation. Although it is accepted that Cotrel-Dubousset instrumentation (CDI) meets these goals, there is concern about the potential risk of trunk imbalance and spinal decompensation during the derotation manoeuvre. The results of 45 patients with idiopathic scoliosis treated with CDI between December 1988 and August 1992 were retrospectively analysed. Mean age was 14.3 years and mean follow-up period was 48.6 months. An average correction of 49.6% was achieved in the major curves. The best results were obtained in King type III curves, with a 69.4% correction. Spinal imbalance was evaluated by measuring lateral trunk shift (LT), shift of head (SH) and shift of stable vertebra (SS). Decompensation was measured by the increase in secondary curves. When all curve types were included, the average preoperative LT value of 1.96 vertebral units (VU) was brought down to 0.91 VU postoperatively, achieving a 55.9% correction. Fourteen patients had an SH value of zero preoperatively and remained balanced after instrumentation. Of the 41 remaining patients, 21 achieved an SH value of zero postoperatively. When all cases were included, the average preoperative SH value was 1.0 VU, which was corrected to 0.42 VU with CDI (69% correction). An average correction of SS of 75.5% was obtained, with the mean preoperative value of 0.73 VU being corrected to 0.19 VU. At the last follow-up visit, a secondary curve had formed above the major curve in one patient, and three patients had a junctional kyphosis. Loss of correction in the frontal plane correlated with loss of correction of LT. The rigid and semiflexible lumbar curves had a tendency to progress when they were not instrumented, especially in type II curves. Junctional kyphosis could be prevented when concave laminar claws were used in the thoraco-lumbar region. It was concluded that spinal decompensation and imbalance could be minimized with careful preoperative planning, avoidance of overcorrection and use of long instrumentation in double major curves.


Subject(s)
Internal Fixators , Scoliosis/surgery , Adolescent , Adult , Child , Female , Follow-Up Studies , Humans , Kyphosis/diagnostic imaging , Kyphosis/etiology , Kyphosis/prevention & control , Male , Radiography , Retrospective Studies , Scoliosis/diagnostic imaging
9.
Arch Orthop Trauma Surg ; 113(2): 86-92, 1994.
Article in English | MEDLINE | ID: mdl-8186055

ABSTRACT

The use of computed tomography and developments in spinal biomechanics have led to a better understanding of vertebral fractures. The disappointing results achieved with conservative treatment have led to an increasing popularity of surgical treatment in the last 15 years. The results of 20 unstable thoracic or lumbar spine fractures treated surgically with Cotrel-Dubousset instrumentation at the First Clinic of Orthopaedics and Traumatology of the Ankara Social Security Hospital between December 1988 and June 1991 were evaluated in this study. The mean follow-up was 31.9 months. The mean sagittal index angle was 23.7 degrees +/- 6.8 degrees preoperatively and was corrected by 67.1 +/- 29.9%, and the thoracolumbar junction angle was brought within physiological limits in 65% of the cases. Postoperatively, the neurological status improved in 15% of the patients and remained unchanged in the rest. It was concluded that the Cotrel-Dubousset instrumentation established vertebral stability in unstable vertebral fractures by forming a rigid frame and restored physiological thoracic and lumbar postural contours due to its highly corrective effect in the sagittal plane.


Subject(s)
Fracture Fixation/instrumentation , Lumbar Vertebrae/injuries , Orthopedic Fixation Devices , Spinal Fractures/surgery , Thoracic Vertebrae/injuries , Adolescent , Adult , Female , Humans , Male , Middle Aged
10.
Eur Spine J ; 3(2): 102-6, 1994.
Article in English | MEDLINE | ID: mdl-7874545

ABSTRACT

The potential for clinical instability following thoracolumbar fractures has evoked a progressive increase in interest in the surgical treatment of unstable thoracolumbar fractures. From September 1988 to October 1991, 44 thoracolumbar burst fractures were treated surgically by the AO Spinal Internal Fixator at the Orthopaedics and Traumatology Clinics of Ankara Social Security Hospital. Mean follow-up period was 28.8 (range 12-48) months. Fourteen (31.8%) of the patients were female, and 30 (68.2%) were male. Postoperatively, the mean anterior vertebral height loss and spinal canal compromise were corrected by 36.5% and 39.9%, respectively. Also, postoperatively 15.9% of improvement was obtained in the mean kyphosis angle. The mean compression angle, which was 19.5 degrees preoperatively, was corrected by 12.3 degrees and came to an average of 7.1 degrees postoperatively. In light of these data, it is suggested that the AO Spinal Internal Fixator effectively restores three-dimensional alignment of the spine and provides a rigid fixation.


Subject(s)
Internal Fixators , Lumbar Vertebrae/injuries , Spinal Fractures/surgery , Thoracic Vertebrae/injuries , Adolescent , Adult , Bone Screws , Female , Humans , Lumbar Vertebrae/surgery , Male , Middle Aged , Postoperative Complications , Retrospective Studies , Spinal Cord Compression/surgery , Spinal Fusion , Thoracic Vertebrae/surgery
11.
Kobe J Med Sci ; 38(4): 233-43, 1992 Aug.
Article in English | MEDLINE | ID: mdl-1469888

ABSTRACT

In this study, we examined 97 patella fractures in which open reduction and internal fixation had been performed at the 1st Orthopaedics and Trauma Clinic of Social Security Ankara Hospital between January 1983 and December 1988. After 24 to 96 months, on an average of 48.4 months follow-up period, the cases were evaluated clinically for knee function complaints and by CT and roentgenography for patellofemoral articulation. In 11 of the patients (11.5) there was patellar displacement, 2 of the patients had patellar tilt (2.1%) and in 14 patients (14.5%) there was malalignment in which 1 patient (1.1%) had both patellar tilt and displacement. This data was obtained by measuring femoral trochlear angle (FTA) and patellar tilt angle (PTA) by CT at various degrees of knee flexion. Thirty-three patients (34%) had slight and 19 patients (19.6%) had severe degenerative changes in the patellofemoral articulation. It is found that there is close relation between the variability of the pain complaints of the patients and the type of the fracture and the time of management and the postoperative rehabilitation.


Subject(s)
Fracture Fixation, Internal , Fractures, Bone/surgery , Pain/etiology , Patella/injuries , Postoperative Complications/physiopathology , Adult , Female , Fractures, Bone/diagnostic imaging , Humans , Knee Joint/diagnostic imaging , Male , Middle Aged , Patella/diagnostic imaging , Patella/surgery , Tomography, X-Ray Computed
12.
J Bone Joint Surg Br ; 74(4): 504-6, 1992 Jul.
Article in English | MEDLINE | ID: mdl-1624505

ABSTRACT

Osteopoikilosis is a rare condition showing characteristic sclerotic lesions on radiographic examination, which are diagnostic for the trait. We report four patients presenting with various complaints and 49 members of their families who later were found to have osteopoikilosis. The mean age of all 53 was 27.5 years and the male:female ratio was 33:20. Most had lesions in the small tubular bones. We studied the epidemiological, clinical and radiological features of these patients and from the pedigrees conclude that the disease is inherited as an autosomal dominant.


Subject(s)
Osteopoikilosis/genetics , Adolescent , Adult , Aged , Child , Consanguinity , Genes, Dominant , Humans , Male , Middle Aged , Osteopoikilosis/diagnostic imaging , Osteopoikilosis/epidemiology , Pedigree , Radiography , Sex Ratio , Turkey/epidemiology
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