ABSTRACT
A 10-month-old female presented with a rapidly growing, painless mass in the right upper eyelid. Due to suspected malignancy, she underwent an urgent biopsy. Histopathological and immunohistochemical analyses revealed nodular fasciitis. Here, we describe the case and perform a literature review of orbital nodular fasciitis in the pediatric population.
Subject(s)
Eyelids , Fasciitis , Humans , Child , Female , Infant , Diagnosis, Differential , Biopsy , Eyelids/pathology , Fasciitis/diagnostic imaging , Fasciitis/surgeryABSTRACT
We report the case of a 29-year-old adult presenting with severe IgA vasculitis, with cutaneous, urologic, and renal manifestations. The late appearance of severe gastrointestinal bleeding dominated the clinical picture, necessitating the administration of tens of units of packed cells and the augmentation of the immunosuppressive protocol. It was not until therapy with intravenous immunoglobulin (IVIG) was introduced that the massive bleeding was controlled. We herein discuss the patient's presentation, the gastrointestinal manifestations of IgA vasculitis, the recommended treatments, and the existent evidence about IVIG therapy.
ABSTRACT
Tumor necrosis factor-α inhibitor-associated adverse cutaneous reactions are common in patients with inflammatory bowel disease. Infection-related dermatoses and psoriasiform eruptions are seen most frequently. We describe a follicular psoriasiform eruption that appeared during treatment with infliximab in two adolescents with Crohn's disease.
Subject(s)
Crohn Disease , Exanthema , Psoriasis , Skin Diseases, Infectious , Adolescent , Antibodies, Monoclonal/adverse effects , Crohn Disease/drug therapy , Exanthema/chemically induced , Humans , Immunologic Factors/adverse effects , Infliximab/adverse effects , Psoriasis/chemically induced , Psoriasis/drug therapy , Psoriasis/pathology , Tumor Necrosis Factor-alphaABSTRACT
This report describes the case of a 43-year-old woman with a right-sided cardiac calcifying fibrous pseudotumor who presented with embolic stroke. This rare clinicopathologic entity should be included in the differential diagnosis of cardiac masses. Tissue diagnosis should be pursued. Management should be tailored to symptoms and feasibility of resection.
Subject(s)
Calcinosis/diagnosis , Echocardiography, Transesophageal/methods , Embolic Stroke/diagnosis , Mediastinal Diseases/diagnosis , Tomography, X-Ray Computed/methods , Adult , Calcinosis/complications , Calcinosis/surgery , Diagnosis, Differential , Embolic Stroke/etiology , Female , Humans , Mediastinal Diseases/complications , Mediastinal Diseases/surgery , Thoracic Surgical Procedures/methodsABSTRACT
Aneurysmal bone cyst (ABC) is a benign locally destructive lesion that usually developed in the bone cavity of bones, less commonly on the surface of cortical bones and very rarely develop outside the bone. There are only 35 reports of extraskeletal aneurysmal bone cyst (ESABC) in the English literature. We report a case of a 12-year-old female with no history of trauma who presented with knee pain. Imaging studies revealed an infrapatellar mass that was fast to calcify during a period of 3 months. MRI showed high T2 center, low T1 signal, and heterogenic enhancement with a rim of low intensity consistent with calcified boarders surrounded by severe soft tissue edema. The lesion was surgically excised, and a histological examination revealed an aneurysmal bone cyst possibly arising within myositis ossificans or heterotopic ossification. In her last follow-up 1.5 years after the surgical excision, the patient was symptom free and without signs of recurrence. To the best of our knowledge, this is the first reported case of an intra-articular ESABC located in the knee.
