Pain Levels Did Not Differ Following Uncomplicated Third Molar Extractions Utilizing Liposomal Bupivacaine Versus Standard Bupivacaine.

PURPOSE: Operations in the oral cavity are often characterized by an acute period of postoperative pain historically mitigated via opioids and other analgesics. The purpose of the study was to determine if liposomal bupivacaine infiltration (LBI) following uncomplicated extraction of bilateral, mandibular third molars will significantly reduce postoperative pain when compared to standard bupivacaine. MATERIALS AND METHODS: The study was designed as a parallel-arm randomized clinical trial. The sample size was calculated for the primary outcome variable: postoperative pain levels measured at 48-hours. Using a power analysis, a sample size of n = 13 for each group was required. Patients meeting the inclusion/exclusion criteria requiring exodontia from November 4, 2018, to June 16, 2022, were recruited out of the oral and maxillofacial surgery clinic. The patients were randomized and divided into 2 groups. Group A was administered 0.50% bupivacaine (with 1:200,000 epinephrine) via infiltration while group B underwent LBI. The primary outcome of interest was postoperative pain levels followed by the secondary outcomes of postoperative narcotic analgesic use, return to oral function, and satisfaction. Patient demographics and characteristics were analyzed as potential covariates utilizing the Fisher exact test and t test for continuous outcomes, respectively. RESULTS: Thirty patients were recruited for the study. The average age of patients receiving the third molar operation was 24.1 ± 5.8 years. Of the 30, 62.5% were female, and 37.5% were male. Seventy-five percent of the patients were Caucasian, 20.8% were African American, and 4.2% were Asian. Forty-eight-hour postoperative interviews revealed mean pain levels of 2.5 ± 2.8 in the control group and 2.9 ± 2.3 in the LBI group (P = .730) as measured on a visual analog scale. The 48-hour postoperative interview identified a mean of 1.9 ± 2.1 narcotic pills used in the control group and 2.5 ± 5.0 pills used in the LBI group (P = .693). CONCLUSIONS: Mandibular LBIs following bilateral mandibular third molar extractions showed no statistically significant advantage over the standard bupivacaine at either time point analyzed. Furthermore, no statistically significant difference was found regarding narcotic use between the 2 groups.

Perception versus reality-findings from a phosphor plate quality assurance study.

OBJECTIVE: The aim of the study was to evaluate the image quality of a photostimulable phosphor (PSP) plate system to determine if image degradation has occurred after a number of clinical uses. STUDY DESIGN: Twenty DIGORA Optime PSP plates (Soredex Orion Corp., Helsinki, Finland) were imaged throughout clinical use. Image quality was assessed by using spatial and contrast resolution through the use of the dental radiographic phantom designed for the Nationwide Evaluation of X-Ray Trends surveys of 1993 and 1999. Spatial resolution was summarized in line pairs per millimeter. The paired t test was used to analyze the contrast wells. The contrast-to-noise ratio (CNR) was calculated to determine the signal-to-noise ratio as another measure of contrast. Descriptive statistics were used to summarize the CNR ratios. RESULTS: Spatial resolution decreased after 48 clinical uses. No significant differences were found for the pairwise comparisons of the contrast wells. No CNR varied by more than two-tenths' value difference. CONCLUSIONS: Digora Optime PSP plates displayed unaffected image quality up to 48 clinical uses. Additional studies are needed to confirm these results and to establish guidelines for appropriate replacement intervals for PSP plates.