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J Pharm Bioallied Sci ; 14(Suppl 1): S863-S867, 2022 Jul.
Article in English | MEDLINE | ID: mdl-36110684

ABSTRACT

Introduction: An essential part of root canal cleaning is irrigating the system to remove any remaining debris and tissue remains. The purpose of root canal therapy is to shape and clean the endodontic space, reduce the bacterial burden, and remove the pulp tissue. In this research, several irrigation solutions with and without sonic irrigation were evaluated to see how quickly tissue dissolves. Method: A tissue sample was taken from a cow (68 ± 3 mg) with no statistically significant difference between groups. All five test tubes in each group were immersed in irrigant, and each group contained one subgroup with five test tubes. Separate weights were recorded for every irrigant that had been passed through the filter paper. Thus, the quantity of pulp dissolved by different irrigating solutions was quantified using a filtering technique. Results: It was revealed that there was a substantial difference between the groups. Sonic and non-sonic irrigation of sodium hypochlorite resulted in a substantial difference in tissue disintegration. Conclusion: This research found that sodium hypochlorite was more effective than EDTA and saline in dissolving pulp. Despite several studies claiming that neem has potent antibacterial activities, tissue dissolution has not been shown in experiments using this herb.

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