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J Am Soc Hypertens ; 8(11): 827-31, 2014 Nov.
Article in English | MEDLINE | ID: mdl-25455008

ABSTRACT

Up to 20% of women with hypertensive pregnancy disorders might persist with chronic hypertension. This study compared clinical and echocardiographic features between women whose hypertension began as hypertensive pregnancy disorders (PH group) and women whose diagnosis of hypertension did not occur during pregnancy (NPH group). Fifty PH and 100 NPH women were cross-sectionally evaluated by clinical, laboratory, and echocardiography analysis, and the groups were matched by duration of hypertension. PH exhibited lower age (46.6 ± 1.4 vs. 65.3 ± 1.1 years; P < .001), but higher systolic (159.8 ± 3.9 vs. 148.0 ± 2.5 mm Hg; P = .009) and diastolic (97.1 ± 2.4 vs. 80.9 ± 1.3 mm Hg; P < .001) blood pressure than NPH, although used more antihypertensive classes (3.4 ± 0.2 vs. 2.6 ± 0.1; P < .001). Furthermore, PH showed higher left ventricular wall thickness and increased prevalence of concentric hypertrophy than NPH after adjusting for age and blood pressure. In conclusion, this study showed that PH may exhibit worse blood pressure control and adverse left ventricular remodeling compared with NPH.


Subject(s)
Hypertension, Pregnancy-Induced/diagnosis , Hypertension, Pregnancy-Induced/drug therapy , Ventricular Dysfunction, Left/diagnostic imaging , Ventricular Remodeling/physiology , Adult , Antihypertensive Agents/therapeutic use , Blood Pressure Determination , Chi-Square Distribution , Confidence Intervals , Cross-Sectional Studies , Echocardiography, Doppler , Female , Follow-Up Studies , Humans , Linear Models , Long-Term Care , Pregnancy , Pregnancy Outcome , Reference Values , Retrospective Studies , Risk Assessment , Severity of Illness Index , Statistics, Nonparametric , Time Factors , Ventricular Dysfunction, Left/epidemiology , Young Adult
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