1.
Org Lett
; 12(18): 4038-41, 2010 Sep 17.
Article
in English
| MEDLINE
| ID: mdl-20735077
ABSTRACT
The copper-catalyzed direct alkynylation of azoles with 1,1-dibromo-1-alkenes as electrophiles is described. These easily accessible substrates are a useful addition to the field of direct alkynylations in an efficient and functional group tolerant reaction to provide a straightforward entry to diverse alkynyl heterocycles.