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1.
Am J Orthod Dentofacial Orthop ; 116(3): 239-53, 1999 Sep.
Article in English | MEDLINE | ID: mdl-10474095

ABSTRACT

This article will present a new soft tissue cephalometric analysis tool. This analysis may be used by the orthodontist and surgeon as an aid in diagnosis and treatment planning. The analysis is a radiographic instrument that was developed directly from the philosophy expressed in Arnett and Bergman "Facial keys to orthodontic diagnosis and treatment planning, Parts I and II" (Am J Orthop Dentofacial Orthod 1993; 103:299-312 and 395-411). The novelty of this approach, as with the "Facial Keys" articles, is an emphasis on soft tissue facial measurement.


Subject(s)
Cephalometry , Face/anatomy & histology , Face/diagnostic imaging , Adult , Cephalometry/methods , Dental Occlusion , Female , Humans , Male , Malocclusion/diagnostic imaging , Patient Care Planning , Radiography , Reference Values , Sex Characteristics , Vertical Dimension
3.
Invest Radiol ; 30(8): 496-501, 1995 Aug.
Article in English | MEDLINE | ID: mdl-8557516

ABSTRACT

RATIONALE AND OBJECTIVES: To prove the feasibility of performing percutaneous transcatheter embolectomy using a funnel-shaped catheter tip and balloon embolectomy catheters. METHODS: A theoretical model is described to assess the influence of the diameter of an introductory device and coaxially introduced embolectomy catheter. A funnel-shaped catheter tip was attached to 7F, 8F, and 9F introductory sheaths. In vitro embolectomy of 5 g and 12 g thrombi was performed with 3F and 4F embolectomy catheters. RESULTS: The number of extractions required was significantly related to the ratio of the diameters of the sheaths and embolectomy catheter shafts. The combination of a 7F sheath with a 4F embolectomy catheter required the greatest number of extractions (8.4 +/- 1.7). The least number of extractions was needed for the combination of a 9F sheath with 4F and 3F embolectomy catheters (1.6 +/- 0.7 and 1.8 +/- 0.4, respectively). CONCLUSIONS: Our results indicate that percutaneous embolectomy with balloon embolectomy catheters is feasible. However, further research is necessary before the final catheter design is chosen.


Subject(s)
Catheterization/instrumentation , Embolectomy/instrumentation , Equipment Design , Humans , Models, Cardiovascular , Thrombectomy/instrumentation
4.
J Nat Prod ; 56(4): 478-88, 1993 Apr.
Article in English | MEDLINE | ID: mdl-7684438

ABSTRACT

Anti-HIV-active polysaccharides and polyphenols were isolated from the brown seaweed Fucus vesiculosus by hot H2O extraction of both the intact and the homogenized algae. This was followed by XAD2 chromatography and by sequential precipitation of the non-adsorbed compounds with glacial HOAc and thereafter with EtOH. The precipitate was solubilized, dialyzed against distilled H2O, and chromatographed on SP-Sephadex C25 and on QAE-Sephadex A25. This was followed by gel filtration on Sephadex G50 and Sephadex G100 and finally by hplc on a Shodex Ionpak S-804 column. For comparison, the commercial product fucoidan, a sulfated algal polysaccharide, was also further purified by the chromatographic techniques mentioned above. The isolated freeze-dried fractions obtained by these procedures were tested for inhibition of both HIV-induced syncytium formation and HIV reverse transcriptase enzyme activity. Some of these fractions inhibited both of these activities at concentrations that were not cytotoxic.


Subject(s)
Antiviral Agents/pharmacology , Flavonoids , HIV/drug effects , Phaeophyceae/chemistry , Phenols/pharmacology , Polymers/pharmacology , Polysaccharides/pharmacology , Antiviral Agents/isolation & purification , Centrifugation , Chromatography, Gel , Chromatography, High Pressure Liquid , Chromatography, Ion Exchange , Exudates and Transudates/chemistry , HIV/enzymology , HIV Reverse Transcriptase , HIV-1/enzymology , Humans , Phenols/isolation & purification , Polymers/isolation & purification , Polyphenols , Polysaccharides/isolation & purification , RNA-Directed DNA Polymerase
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