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1.
Gig Tr Prof Zabol ; (11): 32-3, 1991.
Article in Russian | MEDLINE | ID: mdl-1810826

ABSTRACT

The article contains data on the norming principles for and the biologic action of polymineralic potassium dusts. The analysis and comparison of experimental and clinical data presented potassium ore as a substance characterized by low toxicity and weak fibrogenic action. In animal studies, the general toxic action of potassium aerosols exceeded the fibrogenic effects. MAC was suggested for working zone areas at 5 mg/m3 (3rd class of hazards).


Subject(s)
Dust/adverse effects , Minerals/toxicity , Potassium/toxicity , Animals , Dose-Response Relationship, Drug , Lethal Dose 50 , Maximum Allowable Concentration , Mice , Minerals/poisoning , Poisoning/diagnosis , Potassium/poisoning , Rats , Time Factors
2.
Vrach Delo ; (12): 23-5, 1990 Dec.
Article in Russian | MEDLINE | ID: mdl-1982475

ABSTRACT

Patients with rheumatoid arthritis showed changes of the fatty acid spectrum manifested in a reduction of the polyunsaturated acids (linoleic, linolenic, arachidonic) and an increase of the level of monounsaturated (oleic, palmithooleinic) depended on the course of the disease. Antirheumatic treatment produced a positive effect, especially gold preparations, on normalization of the level of unsaturated fatty acids in rheumatoid arthritis.


Subject(s)
Arthritis, Rheumatoid/blood , Fatty Acids, Unsaturated/blood , Organometallic Compounds , Adrenal Cortex Hormones/therapeutic use , Adult , Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Antirheumatic Agents/therapeutic use , Arthritis, Rheumatoid/drug therapy , Chromatography, Gas , Chronic Disease , Dimercaprol/therapeutic use , Drug Therapy, Combination , Humans , Metalloproteins/therapeutic use , Middle Aged , Organogold Compounds , Propanols , Sulfhydryl Compounds
5.
Vrach Delo ; (4): 55-7, 1989 Apr.
Article in Russian | MEDLINE | ID: mdl-2756689

ABSTRACT

To prevent side-effects of chrysotherapy for rheumatoid arthritis the authors recommend a treatment scheme under corticosteroid protection. The proposed method was used in 56 patients with rheumatoid arthritis. Side-effects manifested in allergic eruptions were noted in 3 patients (5.35%) while in the control group of 34 patients who were treated by chrysotherapy according to the routine method complications were observed in 9 patients (26.47%).


Subject(s)
Arthritis, Rheumatoid/drug therapy , Gold/adverse effects , Dose-Response Relationship, Drug , Drug Therapy, Combination , Female , Gold/administration & dosage , Humans , Male , Prednisolone/administration & dosage , Time Factors
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