ABSTRACT
A Comment on the Letter by S. W. Son, P. Grassberger, and M. Paczuski, Phys. Rev. Lett. 107, 195702 (2011). The authors of the Letter offer a Reply.
ABSTRACT
The pattern of local daily fluctuations of climate fields such as temperatures and geopotential heights is not stable and hard to predict. Surprisingly, we find that the observed relations between such fluctuations in different geographical regions yields a very robust network pattern that remains highly stable during time. Using a new systematic methodology we track the origins of the network stability. It is found that about half of this network stability is due to the spatial 2D embedding of the network, and half is due to physical coupling between climate in different locations. We also find that around the equator, the contribution of the physical coupling is significantly less pronounced compared to off-equatorial regimes. Finally, we show that there is a gradual monotonic modification of the network pattern as a function of altitude difference.
ABSTRACT
Multifocal squamous cell carcinoma in the bronchus of the anterior segment of the right lung and in the subsegmental bronchus of the posterior subsegment of the left upper lobe was diagnosed in a 61-year-old man. The right-sided upper lobectomy followed by Nd:YAG laser photocoagulation of the superficial cancer in the left side resulted in total eradication of the tumor. Subsequent follow-up examinations for three years have revealed no relapse of tumor growth.
Subject(s)
Bronchial Neoplasms/surgery , Carcinoma, Squamous Cell/surgery , Light Coagulation/methods , Bronchoscopy , Follow-Up Studies , Humans , Male , Middle AgedABSTRACT
Translation of free mRNPs and polyribosomal mRNPs from rabbit reticulocytes was studied in a rabbit reticulocyte and wheat germ cell-free systems. It has been shown that translation efficiency of polyribosomal mRNPs and the mRNA isolated from the particles is nearly the same in both systems. At the same time, mRNP's translatability, which is high in the homologous cell-free system, is very low in the system from wheat germs. Translation efficiency of free mRNPs in the wheat germ system can be restored by addition of 0.5 M K CI-wash of rabbit reticulocyte ribosomes. The results testify to the existence of some special repressor repressor/activator system which controls the distribution of mRNA between free mRNPs and polyribosomes in rabbit reticulocytes.
Subject(s)
Gene Expression Regulation , Genes, Regulator , Protein Biosynthesis , RNA, Messenger/genetics , Reticulocytes/metabolism , Ribonucleoproteins/genetics , Animals , Kinetics , Plants/metabolism , Polyribosomes/metabolism , Proteins/genetics , Proteins/isolation & purification , RNA, Messenger/blood , Rabbits , Ribonucleoproteins/blood , Ribonucleoproteins/isolation & purification , Triticum/metabolismABSTRACT
Bronchoscopic operative interventions were performed in 57 patients. We used photocoagulation with neodym-YAG-Laser, electrosurgery with fibroscopic diathermic snare and mechanical removal of endobronchial neoplasms. The most effective method was the laser photocoagulation, which permits removal of benign tumors, carcinoids, massive cicatrical tracheal stenosis and noninvasive bronchial cancer, help in restoring the lumen of main airways in case of nonoperable malignant tumors.
Subject(s)
Airway Obstruction/surgery , Bronchial Neoplasms/surgery , Bronchoscopes , Electrocoagulation/instrumentation , Laser Therapy/instrumentation , Tracheal Neoplasms/surgery , Adolescent , Adult , Aged , Child , Child, Preschool , Combined Modality Therapy , Humans , Middle AgedABSTRACT
A new technique for the measurement of membrane surface potential is proposed and demonstrated. The method is based on the fact that a positively charged styryl dye molecule aggregates when present at high concentration in the Debye layer near a membrane bearing a negative surface potential. The dye in its aggregated form exhibits marked differences in its resonance Raman spectrum relative to the free dye molecules. This method was used to study the potential on the surfaces of the purple membrane that contains the pigment bacteriorhodopsin. A value of -29.5 mV was found for membranes with bacteriorhodopsin in its relaxed, light-adapted state, and the potential decreased to -34.5 mV when most of the bacteriorhodopsin was converted to the M412 intermediate. Because the dye probe does not diffuse through the lipid bilayer, it can be used to probe the potential on the external or internal surface of a vesicle. Thus, we found that the potential on the purple membrane was asymmetric and was localized mainly on the surface that faces the cytoplasm in the cell.
