Subject(s)
Emergencies , Internal Medicine/education , Teaching , Humans , Teaching/methods , Teaching/standardsABSTRACT
A study was made of the vegetative parameters associated with the cardiac rhythm and central hemodynamics in 60 patients with myocardial infarction. In 45 patients the time course of the urinary excretion of catecholamines was examined. Regulation of cardiovascular system in patients with myocardial infarction in different time spells of the disease course was studied in relation to the particular features of the clinical picture and presence of complications.
Subject(s)
Autonomic Nervous System/physiopathology , Cardiovascular System/physiopathology , Myocardial Infarction/physiopathology , Adult , Cardiovascular System/innervation , Catecholamines/urine , Electrocardiography , Humans , Middle Aged , Myocardial Infarction/complications , Myocardial Infarction/urine , Time FactorsABSTRACT
The effect of long-term use of venular and arterial vasodilators (molsidomin and nifedipin) on the clinical course and hemodynamic indices was studied in 52 patients with artificial pacemakers. The choice of vasodilator was based on an acute drug test. In the presence of hypertensive disease the calcium antagonist nifedipin was used, in cases of dilatation of the cardiac compartments molsidomin was used. Combination of both drugs was used in patients in whom the acute drug test did not allow to prefer any of the drugs. It is concluded that three-month's treatment resulted in positive changes of the hemodynamics, reduction of the severity of cardiac insufficiency. Side-effects were practically absent.
Subject(s)
Cardiovascular Diseases/therapy , Pacemaker, Artificial , Vasodilator Agents/therapeutic use , Adult , Aged , Cardiovascular Diseases/physiopathology , Female , Hemodynamics/drug effects , Hemodynamics/physiology , Humans , Male , Middle Aged , Time Factors , Vasodilator Agents/pharmacologyABSTRACT
122 patients with acute myocardial infarction showing a positive antianginal response to nitroglycerin were examined. With the patients under continuous haemodynamic control including pulmonary artery catheterization the circulatory response to various nitrates administered orally, sublingually or transdermally was investigated. A safe time interval was determined for each drug to ensure stability of the attained wedge pressure reduction.
