1.
Clin Pharmacol Ther
; 20(1): 120, 1976 Jul.
Article
in English
| MEDLINE
| ID: mdl-1277720
Subject(s)
Blood Specimen Collection , Quinidine/blood , Blood Proteins/metabolism , Protein Binding
2.
Eur J Clin Pharmacol
; 10(6): 441-4, 1976.
Article
in English
| MEDLINE
| ID: mdl-63371
ABSTRACT
The plasma binding of quinidine and phenytoin has been studied pre- and postoperatively in nine patients submitted to planned gastric surgery. The binding of phenytoin showed a slight and transient reduction, whilst quinidine binding was markedly increased, on average from 78.5% on the day of operation to a maximum of 87.5%, after 2-4 days. The time course of the increase was strikingly parallel to that of the concentration of certain acute phase proteins.
Subject(s)
Blood Proteins/metabolism , Quinidine/blood , Surgical Procedures, Operative , Adult , Alpha-Globulins/metabolism , Female , Humans , Male , Middle Aged , Orosomucoid/metabolism , Phenytoin/blood , Protein Binding , Serum Albumin/metabolism
3.
Acta Pharmacol Toxicol (Copenh)
; 39(5): 570-2, 1976.
Article
in English
| MEDLINE
| ID: mdl-990039
