1.
Ned Tijdschr Geneeskd
; 142(44): 2416-8, 1998 Oct 31.
Article
in Dutch
| MEDLINE
| ID: mdl-9864540
ABSTRACT
The imidazole derivative ketoconazole is approved in the Netherlands for treatment of local and systemic fungal infections. Despite the risk of major hepatic damage, this antimycotic drug is still being used in daily practice for the oral treatment of patients with onychomycosis. Since April 1986, 18 cases of relatively severe hepatic damage in the Netherlands were ascribed to the oral use of ketoconazole for the treatment of onychomycosis, skin infection or vaginal candidiasis. Given the potential risk for the patients concerned, ketoconazole should no longer be prescribed for relatively mild cosmetic disorders such as onychomycosis.
Subject(s)
Antifungal Agents/adverse effects , Chemical and Drug Induced Liver Injury/etiology , Ketoconazole/adverse effects , Onychomycosis/drug therapy , Adolescent , Adult , Adverse Drug Reaction Reporting Systems/statistics & numerical data , Aged , Chemical and Drug Induced Liver Injury/mortality , Female , Humans , Incidence , Liver/pathology , Male , Middle Aged , Necrosis , Netherlands , Onychomycosis/complications , Survival Rate
2.
Phys Rev B Condens Matter
; 51(18): 12763-12770, 1995 May 01.
Article
in English
| MEDLINE
| ID: mdl-9978052
3.
Phys Rev B Condens Matter
; 47(1): 262-272, 1993 Jan 01.
Article
in English
| MEDLINE
| ID: mdl-10004441
4.
5.
Phys Rev B Condens Matter
; 42(1): 1004-1007, 1990 Jul 01.
Article
in English
| MEDLINE
| ID: mdl-9994642
6.
Ned Tijdschr Geneeskd
; 127(12): 492-5, 1983 Mar 19.
Article
in Dutch
| MEDLINE
| ID: mdl-6855926
7.
Ned Tijdschr Geneeskd
; 127(8): 343-4, 1983 Feb 19.
Article
in Dutch
| MEDLINE
| ID: mdl-6300703
8.
Ned Tijdschr Geneeskd
; 116(32): 1385-9, 1972 Aug 05.
Article
in Dutch
| MEDLINE
| ID: mdl-4666138
9.
Ned Tijdschr Geneeskd
; 116(31): 1339-43, 1972 Jul 29.
Article
in Dutch
| MEDLINE
| ID: mdl-4557332
Subject(s)
Heart Neoplasms/diagnosis , Lymphoma, Non-Hodgkin/diagnosis , Aged , Autopsy , Humans , Male , Myocardial Infarction/diagnosis
10.
Ned Tijdschr Geneeskd
; 113(46): 2046-9, 1969 Nov 15.
Article
in Dutch
| MEDLINE
| ID: mdl-5352426