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1.
J Hand Surg Eur Vol ; 35(9): 740-5, 2010 Nov.
Article in English | MEDLINE | ID: mdl-20427404

ABSTRACT

Radioscapholunate arthrodesis is a salvage procedure indicated for osteoarthritis of the radiocarpal joint involving the lunate facet of the radius. This cadaver study examines changes in wrist motion resulting from radioscapholunate arthrodesis, and the effects of surgical techniques to improve the range of motion. Simulated radioscapholunate arthrodesis, distal scaphoidectomy and triquetrectomy were carried out sequentially on six cadaver forearms and measurements (maximum flexion/extension and radial/ulnar deviation) were taken in the intact situation and after each surgical step using a magnetic tracking device. Radioscapholunate arthrodesis diminishes the amplitudes of movements of the wrist in all directions, but range of motion in the radioscapholunate fused wrist improves after scaphoidectomy and improves further after triquetrectomy (88% of original flexion/extension and 98% of original radial/ulnar deviation). Radioscapholunate arthrodesis causes a significant change in kinematics between the hamate and the triquetrum in flexion/extension.


Subject(s)
Lunate Bone/surgery , Radius/surgery , Range of Motion, Articular/physiology , Scaphoid Bone/surgery , Triquetrum Bone/surgery , Wrist Joint/physiology , Aged , Aged, 80 and over , Arthrodesis , Cadaver , Female , Hamate Bone/physiology , Humans , Male , Movement/physiology , Triquetrum Bone/physiology
2.
J Clin Oncol ; 19(1): 231-8, 2001 Jan 01.
Article in English | MEDLINE | ID: mdl-11134217

ABSTRACT

PURPOSE: Tobacco smoking is a risk factor for several cancers. The risk of cutaneous malignancies related to smoking, however, is relatively unknown. We investigated the possible association between smoking and skin cancer. PATIENTS AND METHODS: A hospital-based case-control study was performed that included 161 patients with squamous cell carcinoma, 301 with nodular basal cell carcinoma, 153 with superficial multifocal basal cell carcinoma, 125 with malignant melanoma, and 386 controls. Information on smoking history was collected in personal interviews. Relative risks were estimated using exposure odds ratios from cross-tabulation and logistic regression. RESULTS: An association between smoking and squamous cell carcinoma of the skin was found (relative risk, 2.3; 95% confidence interval, 1.5 to 3.6; P: = .0001), with a higher risk for current smokers (relative risk, 3.3; 95% confidence interval, 1.9 to 5.5) than for former smokers (relative risk, 1.9; 95% confidence interval, 1.2 to 3.0). After adjustment for age, sex, and sun exposure, the relative risk of squamous cell carcinoma was 2.0 (95% confidence interval, 1.2 to 3.2; P: = .008). There was a dose-response relationship with number of cigarettes and pipes smoked. No significant association was found between smoking and nodular basal cell carcinoma, superficial multifocal basal cell carcinoma, or malignant melanoma. CONCLUSION: Tobacco smoking is an independent risk factor for cutaneous squamous cell carcinoma.


Subject(s)
Carcinoma, Basal Cell/etiology , Carcinoma, Squamous Cell/etiology , Melanoma/etiology , Skin Neoplasms/etiology , Smoking/adverse effects , Adult , Aged , Carcinoma, Basal Cell/epidemiology , Carcinoma, Squamous Cell/epidemiology , Case-Control Studies , Dose-Response Relationship, Drug , Female , Humans , Male , Melanoma/epidemiology , Middle Aged , Netherlands/epidemiology , Odds Ratio , Risk , Skin Neoplasms/epidemiology
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