ABSTRACT
El dermatofibroma es una lesión cutánea común en la práctica dermatológica. La manifestación típica es una pápula de crecimiento lento, firme y solitaria. Desde el punto de vista histopatológico, se define en ocasiones como una reacción del tejido conectivo dérmico y en otras como una proliferación neoplásica benigna. En 1990 se publicó por primera vez la existencia de metástasis pulmonares de este tumor. Desde entonces se han recogido en todo el mundo 12 casos de similares características. Presentamos el caso de una mujer joven con un dermatofibroma recidivante en el hombro y metástasis pulmonares bilaterales. Analizamos qué características histológicas del tumor podrían hacer sospechar un comportamiento posterior inusualmente agresivo(AU)
Dermatofibromas are very common skin tumors. Their typical presentation is as a slow-growing, firm, solitary papule. They have been described histopathologically as a reaction of the connective tissue of the skin or as a benign neoplasm. Cases of these tumors metastasizing to the lung were first reported in 1990. Since then 12 cases with similar characteristics have been reported worldwide. We present the case of a young woman with a recurrent dermatofibroma on the shoulder that metastasized to both lungs. We discuss the histologic characteristics of this tumor that could raise suspicion of unusually aggressive behavior(AU)
Subject(s)
Humans , Female , Adult , Histiocytoma, Benign Fibrous , Histiocytoma, Benign Fibrous/complications , Histiocytoma, Benign Fibrous/diagnosis , Histiocytoma, Benign Fibrous/epidemiology , Histiocytoma, Benign Fibrous/etiology , Histiocytoma, Benign Fibrous/surgery , Histiocytoma, Benign Fibrous/therapy , Histiocytoma, Benign Fibrous , Neoplasm Metastasis , Neoplasm Metastasis/therapy , Histology , Case ReportsABSTRACT
Dermatofibromas are very common skin tumors. Their typical presentation is as a slow-growing, firm, solitary papule. They have been described histopathologically as a reaction of the connective tissue of the skin or as a benign neoplasm. Cases of these tumors metastasizing to the lung were first reported in 1990. Since then 12 cases with similar characteristics have been reported worldwide. We present the case of a young woman with a recurrent dermatofibroma on the shoulder that metastasized to both lungs. We discuss the histologic characteristics of this tumor that could raise suspicion of unusually aggressive behavior.
Subject(s)
Histiocytoma, Benign Fibrous/secondary , Lung Neoplasms/secondary , Skin Neoplasms/pathology , Adult , Dermis/pathology , Female , Histiocytoma, Benign Fibrous/diagnostic imaging , Histiocytoma, Benign Fibrous/surgery , Humans , Lung Neoplasms/diagnostic imaging , Lung Neoplasms/surgery , Neoplasm Recurrence, Local/surgery , Pneumonectomy , Positron-Emission Tomography , Shoulder , Skin Neoplasms/surgery , ThoracotomyABSTRACT
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