1.
Anaerobe
; 61: 102099, 2020 Feb.
Article
in English
| MEDLINE
| ID: mdl-31513845
ABSTRACT
Fusobacterium nucleatum is a common oral commensal bacterium capable of severe invasive infections. We report a case of a diffuse bilateral pneumopathy with F. nucleatum-positive blood culture successfully treated by common antibiotics in a patient receiving eculizumab for a drug-induced thrombotic microangiopathy (TMA). It is the first described case of a severe F. nucleatum-associated infection in a patient undergoing terminal complement inhibitor therapy. We suggest providing preventive dental care before eculizumab initiation.
Subject(s)
Antibodies, Monoclonal, Humanized/adverse effects , Bacteremia/etiology , Fusobacterium Infections/diagnosis , Fusobacterium Infections/etiology , Fusobacterium nucleatum , Pneumonia, Bacterial/diagnosis , Pneumonia, Bacterial/etiology , Aged , Antibodies, Monoclonal, Humanized/therapeutic use , Anus Neoplasms/complications , Anus Neoplasms/drug therapy , Complement Inactivating Agents/adverse effects , Complement Inactivating Agents/therapeutic use , Female , Fusobacterium Infections/drug therapy , Fusobacterium nucleatum/genetics , Humans , Pneumonia, Bacterial/drug therapy , Tomography, X-Ray Computed , Ultrasonography, Doppler
2.
Ann Phys Rehabil Med
; 61(6): 419-420, 2018 Nov.
Article
in English
| MEDLINE
| ID: mdl-29438827
