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1.
Ann Pathol ; 44(1): 69-74, 2024 Feb.
Article in French | MEDLINE | ID: mdl-38216436

ABSTRACT

Langerhans cell histiocytosis (LCH) is a disease whose physiopathology remains unclear, involving both inflammatory processes and clonal proliferation. It is observable at any given age, although about ten times more frequent in children than adults. Hepatic involvement is not rare, mostly part of a systemic disease, and linked to a poor prognosis. We report here a case of LCH with solitary hepatic involvement in a 74 year-old patient. This case demonstrated molecular anomaly of the MAPK pathway, BRAF N486_P490del. Through this observation, we precise the epidemiological and histological aspects and diagnostic criteria of this rare disease.


Subject(s)
Histiocytosis, Langerhans-Cell , Aged , Humans , Histiocytosis, Langerhans-Cell/diagnosis , Liver/pathology , Rare Diseases
2.
Ann Vasc Surg ; 79: 443.e1-443.e3, 2022 Feb.
Article in English | MEDLINE | ID: mdl-34656715

ABSTRACT

Abdominal trauma leads rarely to severe renal injury such as acquired arterioveinous fistula. Here, we present the case of a 46-year-old man with a history of suicide attempt by a gunshot in the abdomen. At that time, explorative laparotomy was unremarkable. He consulted 23 years later for chronic left lumbar pain and was diagnosed with an arterioveinous fistula of left renal vessels with a-10-cm aneurysm of the left renal artery. We performed a left nephrectomy and endovascular clamping was the best option to manage this giant aneurysm in a hostile abdomen.


Subject(s)
Abdominal Injuries/etiology , Aneurysm/etiology , Arteriovenous Fistula/etiology , Renal Artery/injuries , Renal Veins/injuries , Vascular System Injuries/etiology , Wounds, Gunshot/complications , Abdominal Injuries/diagnostic imaging , Abdominal Injuries/surgery , Aneurysm/diagnostic imaging , Aneurysm/surgery , Arteriovenous Fistula/diagnostic imaging , Arteriovenous Fistula/surgery , Asymptomatic Diseases , Constriction , Endovascular Procedures , Humans , Male , Middle Aged , Nephrectomy , Renal Artery/diagnostic imaging , Renal Artery/surgery , Renal Veins/diagnostic imaging , Renal Veins/surgery , Suicide, Attempted , Time Factors , Vascular System Injuries/diagnostic imaging , Vascular System Injuries/surgery
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