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Hepatitis C in Children and Adolescents of a Brazilian Tertiary Center: Identifying Patients Eligible for Direct-Acting Antivirals.
Hirsch, Camila Bellettini; Pereira, Maria Fernanda Bádue; Benevides, Gabriel Nuncio; Bernardes, Tamires Miranda; Palandri, Giovanna Gavros; Bastos, Karina Lucio de Medeiros; Toma, Ricardo Katsuya; de Azevedo, Ramiro Anthero; Marques, Heloisa Helena de Sousa.
Pediatr Infect Dis J ; 39(9): e276-e278, 2020 09.
Article in English | MEDLINE | ID: mdl-32496409

ABSTRACT

We evaluated 113 pediatric patients with chronic hepatitis C from 2009 to 2019 at a Brazilian tertiary center. Seventy patients received pegylated-interferon treatment. The sustained virologic response was 61.4%, and 92.8% reported side effects. Currently, we are following 39 patients with chronic hepatitis C, 24 of whom are eligible for treatment with direct-acting antivirals according to Brazilian recommendations.


Subject(s)
Antiviral Agents/therapeutic use , Hepatitis C, Chronic/drug therapy , Sustained Virologic Response , Tertiary Care Centers/statistics & numerical data , Adolescent , Antiviral Agents/standards , Brazil , Child , Child, Preschool , Drug Therapy, Combination , Female , Hepacivirus/drug effects , Humans , Infant , Infant, Newborn , Interferon-alpha/therapeutic use , Male , Retrospective Studies
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