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Antimicrob Agents Chemother ; 10(2): 283-7, 1976 Aug.
Article in English | MEDLINE | ID: mdl-984770

ABSTRACT

Pharmacokinetic parameters were calculated from intravenous data based upon a two-compartment open model. These parameters were subsequently used to determine the absorption rates and bioavailability of cephradine administered intramuscularly and orally. The results indicate that cephradine obeys dose-independent kinetics and that biological availability is complete from all dosage forms.


Subject(s)
Cephalosporins/blood , Cephradine/blood , Administration, Oral , Adult , Biological Availability , Cephradine/administration & dosage , Humans , Injections, Intramuscular , Injections, Intravenous , Kinetics , Male
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