ABSTRACT
BACKGROUND AND PURPOSE: A study was conducted to compare the quality of life (QOL) of surgically versus endovascularly treated patients with ruptured cerebral aneurysms. METHODS: We treated 45 patients surgically (surgical clipping [SC] group) and 44 by endovascular therapy (coil embolization [CE] group). A standardized test of QOL and a structured interview were employed to assess changes 1 year after subarachnoid hemorrhage (SAH). One neurosurgical team using the same treatment protocols treated all patients. The SC and CE groups did not differ significantly in age, sex, education, aneurysm size, Hunt and Hess grade, Glasgow outcome scale (GOS) score, and intelligence quotient (IQ). RESULTS: Generally, the patients reported psychological changes (impairment in memory, 47%; concentration, 20%; and ability to learn new things, 12%), which they subjectively related to SAH. On the one hand, 31% of the patients believed that close relatives noticed changes in their psychological condition as a result of the intervention. On the other hand, 61% reported an unaltered economic situation, 51% were well adjusted in work, and 70% claimed their family relationships remained unchanged. In comparison with the controls, patients claimed to have lower QOL in the areas of sexuality, love, psychic well-being, physical autonomy, and health. No differences in QOL were found between the SE and CE groups. CONCLUSIONS: The differences in QOL in the patients treated by either coiling or clipping were small and nonsignificant. Participants in both groups mentioned lower QOL in the areas of intimate relationships and health.
Subject(s)
Endovascular Procedures/methods , Neurosurgical Procedures/methods , Subarachnoid Hemorrhage/psychology , Subarachnoid Hemorrhage/surgery , Adult , Aneurysm, Ruptured/surgery , Attention , Embolization, Therapeutic , Female , Follow-Up Studies , Glasgow Outcome Scale , Health Status , Humans , Intelligence Tests , Interpersonal Relations , Learning Disabilities/etiology , Male , Memory Disorders/etiology , Middle Aged , Neuropsychological Tests , Personal Autonomy , Quality of Life , Sexuality , Treatment Outcome , Young AdultABSTRACT
BACKGROUND AND PURPOSE: This prospective study investigated whether surgery or endovascular treatment for unruptured intracranial aneurysms (UIAs) affects cognitive functions. METHODS: Four neuropsychological variables from an Auditory Verbal Learning Test (overall capacity of verbal memory and delayed recall) and a Trail Making Test (psychomotor speed and cognitive flexibility) were investigated before and 1 year after treatment for UIAs in 65 patients < 61 years of age. This cohort consists of 15 men and 50 women aged 15-60 (mean age 44.9) years. RESULTS: Group-rate analysis showed a non-significant increase in post-treatment scores in the four neuropsychological variables. In addition, no significant differences were found between the surgical clipping (SC) and endovascular coiling (EC) group. Event-rate analysis demonstrated that two patients from the EC and one from the SC group developed cognitive impairment after treatment. CONCLUSIONS: Surgical and endovascular repair for UIAs do not impair cognition in patients without postoperative restrictions in lifestyle.
Subject(s)
Cognition Disorders/etiology , Endovascular Procedures/methods , Intracranial Aneurysm/psychology , Intracranial Aneurysm/surgery , Adolescent , Adult , Female , Humans , Male , Middle Aged , Neuropsychological Tests , Postoperative Care , Preoperative Care , Prospective Studies , Psychomotor Disorders/etiology , Young AdultABSTRACT
BACKGROUND: Verbal memory is an essential cognitive ability with scope for adequate treatment of information and for orientation in everyday life. Our study is centered on memory performance in the wake of treatment for ruptured intracranial aneurysm. METHODS: Three psychological tests were performed: (1) within a month of the neurosurgical intervention, (2) 1 year and (3) 5-7 years after the ruptured aneurysm treatment. Under comparison are the overall results of tests for verbal memory capacity in a cohort of patients (N = 59) and in the control group. RESULTS: Three post-treatment measurements revealed a persistent deficit of verbal memory. The cohort's average performance improved from -1.3 SD (standard deviation) below the average of the norm to -0.5 SD below the norm at the second test 1 year after treatment, while at the third test the deficit had worsened to -0.68 SD. Similarly, testing for long-term recovery at 5-7 years postoperatively showed the patients' performances to be 2/3 SD below the average of the general population. CONCLUSIONS: The results of the study imply the need for long-term rehabilitation of memory in this particular group of patients.
