ABSTRACT
Establishing an S-scheme heterojunction is a promising method for increasing the photocatalytic activity of synthetic materials. In this study, nitrogen-doped g-C3N5/TiO2 S-scheme photocatalysts have been synthesized and examined for photocatalytic hydrogen production using thermal decomposition methods. Nitrogen-doped g-C3N5/TiO2 composites performed better than pure nitrogen-doped g-C3N5 and TiO2 alone. Using experiments and density functional theory (DFT) calculations, nitrogen (N) doping was identified as being introduced by replacing the carbon (C) atoms in the matrix of g-C3N5. In addition to its narrow band gap, N-doped g-C3N5 showed efficient carrier separation and charge transfer, resulting in the enhanced absorption of visible light and photocatalytic activity. DFT, XPS, optical property characteristics, and PL spectra confirmed these findings, which were attributed to the successful nitrogen doping, and the composite was proven to be a potential candidate for photocatalytic hydrogen generation under light irradiation. The quantity of H2 produced from the nitrogen-doped g-C3N5/TiO2 composite for 3 hours (3515.1 µmol g-1) was about three times that of N-doped g-C3N5. The H2 production percentage of the nitrogen-doped g-C3N5/TiO2 catalyst with Pt as the cocatalyst was improved by nearly ten times as compared to N-doped g-C3N5/TiO2 without a cocatalyst. Herein, we report the successful preparation of the N-doped g-C3N5/TiO2 S-scheme heterojunction and highlight a simple and efficient catalyst for energy storage requirements and environmental monitoring.
ABSTRACT
Rising concerns of pesticide-induced neurotoxicity and neurodegenerative diseases like Parkinson's, Alzheimer's, and Multiple Sclerosis, are exacerbated by overexposure to contaminated waterbodies. Therefore, evaluating the risk accurately requires reliable monitoring of related biomarkers like dopamine (DA) through electrochemical detection. Layered double hydroxides (LDHs) have shown great potential in sensors. However, to meet the challenges of rapid detection of large patient cohorts in real-time biological media, they should be further tailored to display superior analytical readouts. Herein, a ternary LDH (Ni2CoMn0.5) was integrated with the sheets of thermally reduced graphene oxide (trGO), to expose more highly active edge planes of the LDH, as opposed to its generally observed inert basal planes. The improvement in detection performance through such a modulated structure-property is a prospect that hasn't been previously explored for any other LDH-based materials employed in sensing applications. The 2 folds superior electrochemical activity exhibited by the face-on oriented LDH with trGO as compared to the pristine LDH material was further employed for direct detection of DA in real blood plasma samples. Moreover, the designed sensor exhibited exceptional selectivity towards the detection of DA with a limit of detection of 34.6 nM for a wide dynamic range of 0.001-5 mM with exceptional stability retaining 88.56% of the initial current even after storage in ambient conditions for 30 days.
Subject(s)
Dopamine , Electrochemical Techniques , Humans , Electrochemical Techniques/methods , Hydroxides/chemistryABSTRACT
Herein, an innovative way of designing a star-shaped gold nanoconfined multiwalled carbon nanotube-engineered sensoring interface (AuNS@MWCNT//GCE) is demonstrated for quantification of methionine (MTH); a proof of concept for lung metastasis. The customization of the AuNS@MWCNT is assisted by surface electrochemistry and thoroughly discussed using state-of-the-art analytical advances. Micrograph analysis proves the protrusion of nanotips on the surface of potentiostatically synthesized AuNPs and validates the hypothesis of Turkevich seed (AuNP)-mediated formation of AuNSs. In addition, a facile synthesis of electropotential-assisted transformation of MWCNTs to luminescent nitrogen-doped graphene quantum dots (Nd-GQDs avg. â¼4.3 nm) is unveiled. The sensor elucidates two dynamic responses as a function of CMTH ranging from 2 to 250 µM and from 250 to 3000 µM with a detection limit (DL) of â¼0.20 µM, and is robust to interferents except for tiny response of a similar -SH group bearing Cys (<9.00%). The high sensitivity (0.44 µA·µM-1·cm-2) and selectivity of the sensor can be attributed to the strong hybridization of the Au nanoparticle with the sp2 C atom of the MWCNTs, which makes them a powerful electron acceptor for Au-SH-MTH interaction as evidenced by density functional theory (DFT) calculations. The validation of the acceptable recovery of MTH in real serum and pharma samples by standard McCarthy-Sullivan assay reveals the holding of great promise to provide valuable information for early diagnosis as well as assessing the therapeutic consequence of lung metastasis.
Subject(s)
Lung Neoplasms , Metal Nanoparticles , Nanotubes, Carbon , Humans , Gold , BiomarkersABSTRACT
Due to their appropriate physicochemical properties, nanoparticles are used in nanomedicine to develop drug delivery systems for anticancer therapy. In biomedical applications, metal oxide nanoparticles are used as powerful and flexible multipurpose agents. This work described a green synthesis of Y2O3 nanoparticles (NPs) using the sol-gel technique with the use of aqueous leaf extracts of Lantana camara L (LC). These nanoparticles were characterized with the aid of different methods, including UV, X-ray diffraction (XRD), Fourier transformed infrared spectroscopy (FTIR), transmitted electron microscopy (TEM), and photocatalytic degradation. Y2O3 nanoparticles showed excellent antibacterial activity against Gram-positive Bacillus subtilis and Gram-negative Escherichia coli with a 10 to 15 mm inhibitory zone. Green Y2O3 NPs were released with a 4 h lag time and 80% sustained release rate, indicating that they could be used in drug delivery. In addition, the bioavailability of green Y2O3 NPs was investigated using cell viability in cervical cancer cell lines. These green-synthesized Y2O3 NPs demonstrated photocatalytic degradation, antibacterial, and anticancer properties.
