Prevalent coinfection and associated factors for Hepatitis B, Hepatitis C, and Human Immunodeficiency Virus in patients submitted to renal replacement therapy: A cross-sectional study of 21 dialysis units in the State of Mexico.

BACKGROUND: Chronic kidney disease (CKD) predispose to viral coinfections in patients submitted to renal replacement therapy (RRT); nevertheless, few reports have been performed to elucidate the current epidemiology within this population in Mexico. AIM: To estimate the prevalence of HBV, HCV, and HIV coinfection and to explore factors associated with prevalent coinfection in patients living with renal failure undergoing to RRT. METHODS: A multicenter cross-sectional recruitment across 21 units at the Mexican Institute of Social Security (IMSS) at the State of Mexico was performed during 2019. A standardized clinical questionnaire was performed to elucidate individual and relatives-related conditions. A treatment facility questionnaire was applied to the chief responsible of each unit to explore treatment facility variables. Serological testing, clinical, biochemical, and anthropometrical parameters were extracted from clinical records. RESULT: In 1,304 patients (57.5% male, mean age 45.5 (SD: 15.6) years, and 95.8% in hemodialysis), the prevalence of any viral coinfection was 3.14% (95% CI: 2.32%-4.23%). The highest viral coinfection prevalence were for HCV, HBV, and HIV, in which men and subjects diagnosed after 2010's had the highest rates. We identify that being submitted to peritoneal dialysis, being treated in a surrogated dialysis center and living with a close relative with prior hepatitis coinfection were associated factors for any viral coinfection. CONCLUSION: In patients submitted to RRT, the prevalence of viral coinfection remains high compared with general population. Screening strategies, medical awareness and targeted public healthcare policies should prioritize better care practices within patients submitted to RRT in Mexico.

Prevalence and characterization of undiagnosed arterial hypertension in the eastern zone of Mexico.

Arterial hypertension is considered a public health problem with severe consequences at an individual and public health levels. However, there is a lack of information regarding its characterization in Mexico. The objective of this study is to estimate the proportion of undiagnosed arterial hypertension (UAH) and the overall prevalence and clinical management of arterial hypertension within the Eastern Zone of Mexico. Additionally, we explore associated factors related with both UAH and uncontrolled arterial hypertension. We obtained information from the May Measure Month (MMM) 2019 study. People were asked for cardiovascular risk factors and blood pressure was measured according to the protocols of the European Society of Hypertension (ESH). Data from 5901 subjects were extracted: 76.04% from the Eastern Zone of the State of Mexico. The overall prevalence of hypertension was 32.4% (95% CI 31.2-33.6). From all subjects living with hypertension, 28.3% had UAH, 22.1% had previous diagnosis but were untreated; 29.3% were treated but had uncontrolled hypertension. Younger men adults living in the State of Michoacán had increased proportion of UAH and untreated hypertension. We observed that male sex, age, obesity, living at Michoacán were risk factors for UAH. Finally, male sex, diabetes, and living at Michoacán were related risk conditions for having uncontrolled arterial hypertension. In summary, there is a high proportion of UAH in Easter Zone of Mexico. Younger adults had higher proportion of UAH and untreated hypertension profiles. Efficient actions are required to make a timely diagnosis in the young adult population to prevent long-term complications.

Bibliometric analysis of research reports: IMSS Southern Research Forum.

INTRODUCCIÓN: La Coordinación de Investigación en Salud del Instituto Mexicano del Seguro Social promueve acciones para la realización del Foro Sur de Investigación en Salud del Instituto Mexicano del Seguro Social (FSIS-IMSS), entre las que destacan la presentación de reportes de investigación. OBJETIVO: Analizar la actividad científica del FSIS-IMSS de 1995 a 2018 a través de los reportes de investigación publicados en el marco del Foro Sur. MATERIAL Y MÉTODOS: Estudio bibliométrico de los reportes de investigación publicados. Se elaboró una base de datos en el gestor EndNote X8 y se exportó a Excel para su análisis. Se empleó el Manual Metodológico de Indicadores Médicos 2017 para estandarizar la temática de investigación. Variables: productividad, colaboración, concentración y dispersión. Análisis: frecuencia y media, pruebas de Olmstead Tukey modificada por García de León, Shapiro-Wilk, r de Spearman y ji al cuadrado. RESULTADOS: 15,249 investigadores (el 53% mujeres) publicaron 6166 reportes de investigación. Ley de Price con ecuación: y = 130.13 e0.048x. Ley de Lotka conforma 45 grandes investigadores, 2899 medianos y 12,305 pequeños (p < 0.05). Colaboración alta: índice Subramanyan 0.8860 y tres autores como extensión (p < 0.05). Concentración temática moderada: índice Price 0.4922. Categoría temática dominante: diabetes mellitus. El modelo de Bradford explica la contribución de investigadores adscritos a 58 tipos de unidades, 10/58 aportaron 2054 reportes frente a 2061 de 57/58. CONCLUSIONES: La actividad científica del FSIS-IMSS en 1995-2018 tuvo mayor participación de mujeres y colaboración múltiple. Se observa una extensión de reportes constante de crecimiento exponencial y concentración de autores de reporte único. Discreta dispersión temática. Alta productividad de las unidades médicas de alta especialidad, los hospitales generales de zona y las instituciones educativas. BACKGROUND: The Health Research Coordination of the Mexican Institute of the Mexican Institute of Social Security promotes actions for the realization of the Southern Forum of Health Research of the Mexican Institute of Social Security (FSIS-IMSS), among which the presentation of research reports stands out. OBJECTIVE: Analyze the scientific activity of FSIS-IMSS from 1995 to 2018, through the research reports published in the framework of the Southern Forum. MATERIAL AND METHODS: Bibliometric study of published research reports. The database was created in the EndNote X8 manager and exported to Excel for analysis. Methodological Manual of Medical Indicators 2017 used to standardize research topics. Variables: productivity; collaboration; concentration; dispersion. Analysis: frequency, mean. Olmstead Tukey tests ­modified by García de León, Shapiro Wilk, r Spearman, Chi s­quare. RESULTS: 15,249 researchers (53% women) published 6166 scientific reports. Law of Price with equation: y = 130.13 e0.048x. Lotka's law consists of 45 large researchers, 2899 medium and 12,305 small (p < 0.05). High collaboration: Subramanyan index 0.8860 and three authors as extension (p < 0.05). Moderate thematic concentration: Price index 0.4922. Olmstead Tukey test modified by García de León exposes dominant thematic category: diabetes mellitus. Model of Bradford explains: 10/58 different types of units according to secondment of researchers contributed 2054 reports; 57/58 contributed 2061. CONCLUSIONS: Scientific activity of the FSIS-IMSS, from 1995-2018 shows greater participation of women, multiple collaboration and extension of constant reports of exponential growth and concentration of single report authors. Discrete thematic dispersion. High productivity of high specialty medical units, general zone hospitals and educational ­institutions.