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Assessment of spontaneous fluctuations of viral load in untreated patients with chronic hepatitis C by two standardized quantitation methods: branched DNA and Amplicor Monitor.

Halfon, P; Bourlière, M; Halimi, G; Khiri, H; Bertezene, P; Portal, I; Botta-Fridlund, D; Gauthier, A P; Jullien, M; Feryn, J M; Gerolami, V; Cartouzou, G.

J Clin Microbiol ; 36(7): 2073-5, 1998 Jul.

Article in English | MEDLINE | ID: mdl-9650965

ABSTRACT

Quantitation of hepatitis C virus (HCV) RNA in serum has been used to predict and monitor the efficacy of interferon therapy in chronic HCV infection. We prospectively studied the fluctuation of viremia by a longitudinal follow-up of HCV RNA levels for 2 months in six untreated patients. Spontaneous fluctuations of HCV RNA ranged from 2.8- to 5.7-fold with branched DNA assay and from 2.9- to 5.6-fold with Monitor. These large spontaneous fluctuations (up to 0.75 log), observed daily, weekly, and monthly, raise doubt about the clinical value of a single assessment of pretherapeutic viremia.

Subject(s)

Hepacivirus/physiology , Hepatitis C, Chronic/virology , Polymerase Chain Reaction/methods , RNA, Viral/blood , Adult , Female , Humans , Male , Middle Aged , Prospective Studies , Viral Load

[Lacrimal involvement in viral keratoconjunctivitis. Preventive and therapeutic consequences]. / Atteinte lacrymale dans les kérato-conjonctivites virale. Conséquences thérapeutiques préventives et curatives.

Bertezene, P; Erraziqi, A; Lecaillon-Thibon, B; Delpech, N; Marti, Y.

Bull Soc Ophtalmol Fr ; 89(11): 1293-6, 1989 Nov.

Article in French | MEDLINE | ID: mdl-2630134

Subject(s)

Keratoconjunctivitis/complications , Lacrimal Apparatus Diseases/etiology , Virus Diseases/complications , Aged , Aged, 80 and over , Electrophoresis , Female , Humans , Keratoconjunctivitis/drug therapy , Lacrimal Apparatus Diseases/drug therapy , Male , Prognosis , Tears/analysis , Virus Diseases/drug therapy

[Athletic injuries of the orbit and eyelid]. / Traumatologie sportive de l'orbite et de la paupière.

Rolland, A; Bertezene, P; Davet, J M; Dupeyron, G; Lecaillon-Thibon, B.

Bull Soc Ophtalmol Fr ; 80(6-7): 529-32, 1980.

Article in French | MEDLINE | ID: mdl-7408099

Subject(s)

Athletic Injuries , Eyelids/injuries , Orbit/injuries , Athletic Injuries/diagnosis , Athletic Injuries/surgery , Humans

[2 unusual ophthalmological complications of craniofacial injuries]. / Deux complicatons ophtalmologiques inhabituelles des traumatismes cranio-faciaux.

Bertezene, P; Borne, G; Davet, J M; Dupeyron, G; Lecaillon-Thibon, B; Payrot, C; Rolland, A.

Bull Soc Ophtalmol Fr ; 79(11-12): 959-61, 1979.

Article in French | MEDLINE | ID: mdl-552958

Subject(s)

Facial Bones/injuries , Hemianopsia/etiology , Lacrimal Duct Obstruction/etiology , Skull Fractures/complications , Adult , Humans , Male , Middle Aged

[25 maxillomalar fractures : value of the use of lyophilized dura mater in the reconstruction of the orbital floor]. / A propos de 25 fractures maxillo-malaires : intérêt de l'utilisation de dure mère lyophilisée dans la restauration du plancher orbitaire.

Bertezene, P; Davet, J M; Dupeyron, G; Thibon, B L; Rolland, A.

Bull Soc Ophtalmol Fr ; 79(4-5): 309-11, 1979.

Article in French | MEDLINE | ID: mdl-393424

Subject(s)

Dura Mater/transplantation , Maxillary Fractures/surgery , Orbit/surgery , Zygomatic Fractures/surgery , Adult , Bone Transplantation , Female , Freeze Drying , Humans , Male , Transplantation, Homologous

[Endothelial dystrophies and cataracts]. / Dystrophies endothéliales et cataractes

Bertezène, P; Lecaillon-Thibon, B.

Bull Soc Ophtalmol Fr ; 73(2): 277-86, 1973 Feb.

Article in French | MEDLINE | ID: mdl-4603518

Subject(s)

Cataract/complications , Corneal Dystrophies, Hereditary/complications , Corneal Transplantation , Cataract Extraction , Female , Glaucoma/etiology , Humans , Keratitis/etiology , Male , Methods , Postoperative Complications , Transplantation, Autologous

[A case of Tay-Sachs disease]. / A propos d'un cas de maladie de Tay-Sachs.

Bertezène, P.

Bull Soc Ophtalmol Fr ; 72(7): 697-702, 1972.

Article in French | MEDLINE | ID: mdl-4661334

Subject(s)

Eye Manifestations , Lipidoses , Retina/pathology , Brain/pathology , Brain Chemistry , Female , Gangliosides/analysis , Humans , Infant , Lipidoses/diagnosis , Lipidoses/pathology

[2 cases of "blow out" fracture of the orbit]. / Deux cas de "blow out" fracture de l'orbite.

Boudet, C; Bertezene, P.

Bull Soc Ophtalmol Fr ; 68(9): 793-801, 1968.

Article in French | MEDLINE | ID: mdl-5713025

Subject(s)

Fractures, Bone , Orbit/injuries , Adolescent , Athletic Injuries , Child , Eye Injuries , Female , Humans , Male

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