ABSTRACT
The present work deals with a series of 28 patients (a total of 31 hips) suffering from coxarthrosis in dysplasia of the hip. All patients had undergone arthroplasty where an autograft of cortico-cancellous bone was taken from the head of the patientís femur. In 21 of these hips the prosthetic components were not cemented while the other 10 cases were. The patients (average age 57 years 5 months) underwent radiography and were clinically evaluated using the Harris Hip Score. The average follow-up was 6 years and 7 months. In the 10 hips which had been cemented, the average pre-operative Harris Hip Score was 46.9 points (range 24-85) while it was 80.5 upon check-up (range 50-98). In the 21 hips which were not cemented the average pre-operative Harris Hip Score was 44.3 points (range 21-62) while, at the time of check-up it was 90.8 (range 60-100). Only in 3 cases (9.67%) did the cotyloid portion require reoperation because of mobilization. In all cases (100%) the graft integrated perfectly with the host bone. The present study provides encouraging data regarding the use of autografts of cortico-cancellous bone taken from the head of the femur during hip replacement in patients with coxarthrosis in dysplasia of the hip. No differences were seen between the cemented and non cemented prostheses.
Subject(s)
Acetabulum/surgery , Arthroplasty, Replacement, Hip/methods , Femur Head/transplantation , Hip Dislocation, Congenital/surgery , Osteoarthritis, Hip/surgery , Adult , Aged , Bone Cements , Female , Follow-Up Studies , Hip Dislocation, Congenital/complications , Humans , Male , Middle Aged , Osseointegration , Osteoarthritis, Hip/etiology , Retrospective Studies , Severity of Illness Index , Transplantation, Autologous , Treatment OutcomeABSTRACT
Complex segregation analysis was conducted in a sample of 171 pedigrees collected through probands affected by non-syndromic dysplasia of the hip (CDH) treated in Ferrara's CDH Centre in the period 1991-6. The analysis favoured a two-locus model, in which the accepted segregation model at the major locus was compatible with recessive transmission, with a gene frequency of the deleterious allele of around 0.20. For the other locus, among the Mendelian hypotheses tested, the recessive model turned out to be the most parsimonious. When ultrasonographic level was examined as an indication of severity, a significant improvement in the fit of the model was observed, giving clear evidence that information on the severity of CDH is important for a better definition of the hereditary transmission model.
Subject(s)
Chromosome Mapping , Genetic Heterogeneity , Hip Dislocation, Congenital/genetics , Models, Genetic , Child , Chromosome Segregation , Female , Humans , Male , Nuclear Family , PedigreeABSTRACT
The progressive aging of the population, a phenomenon that is common to all Western societies, means an increase in the number of patients aged over 80 years requiring total hip replacement. It is the purpose of this study to report our experience in the use of total hip replacement for the treatment of patients aged over 80 years. The study is retrospective, and it was conducted on a group of 27 patients, for a total of 33 hips. An analysis of the results led us to conclude that there are no differences in indications for total hip replacement in patients aged over 80 years as compared to younger subjects. Nonetheless, it is important to carefully evaluate the general conditions of these patients, prior to surgery, because failure may have dramatic consequences.
