ABSTRACT
BACKGROUND AND AIMS: The authors performed a retrospective analysis of 682 patients attending the Menopause Centre from 1994 to today. These patients were referred for a wide variety of symptoms occurring in premenopause and menopause. METHODS: All patients initially underwent general screening which was followed by appropriate therapy on the basis of objective examination, blood chemical and instrumental tests, and the subjective clinical situation. RESULTS AND CONCLUSIONS: It was found that the most frequently used treatment was sequential or combined oestroprogestin replacement treatment (63%), with tibolone in 9% of cases and veralipride in 5%. The best results from the point of view of the improved wellbeing of the woman were obtained using HRT and tibolone.
Subject(s)
Estrogen Replacement Therapy , Menopause , Female , Humans , Life Style , Menopause/physiology , Menopause/psychology , Middle AgedABSTRACT
BACKGROUND: The differential diagnosis between benign and malignant pelvic masses is still difficult and is based on clinical semeiotics and echography, whereas a reliable diagnosis can only be obtained by histological analysis. METHODS: A total of 40 patients were examined using transvaginal Doppler echoflowmetry which was used to evaluate the vascular distribution and intralesional and perilesional flowmetric values. These values were then compared with oncogenic markers and with histological tests of the neoformations. RESULTS: Histological analysis revealed that a flow with high PI is a marker of benignancy, whereas a low PI value tends to show malignancy. On the contrary oncogenic markers reveal a high level of sensitivity but low specificity, especially CA 125.
Subject(s)
Biomarkers, Tumor , Laser-Doppler Flowmetry , Pelvic Neoplasms/diagnostic imaging , Adnexal Diseases/diagnosis , Adnexal Diseases/diagnostic imaging , CA-125 Antigen/immunology , Diagnosis, Differential , Female , Humans , Pelvic Neoplasms/immunology , UltrasonographyABSTRACT
Two cases of cystic microglandular hyperplasia of the cervix, one with exocervical and the other with endocervical site are reported. These clinical cases were presented because of the rarity of this type of lesion and because of the difficulty of differentiating them from a well-differentiated cervical adenocarcinoma; noteworthy is the lack of a progestinic climate in the two patients, a situation that is considered highly predisposing.
