[Electrocardiography in the detection and prevention of asymptomatic coronary heart disease]. / Znacaj elektrokardiografije u detekciji i prevenciji asimptomatske koronarne bolesti srca.

This article presents relevant scientific facts about the role of ECG as a screening test in detection and prevention of asymptomatic coronary artery disease. The article represents an analytic study of great number of scientific publications from this area; only the most significant articles were used as references which can be used both as a confirmation of the statements in the article and as an initial guideline for those who are interested in more in-depth analysis of this problem. According to the conclusions of the majority of authors, ECG does not have great practical or medical value as a screening test for asymptomatic coronary artery disease because, with its application, reductions in morbidity and mortality were proven to be insignificant. ECG exercise testing is more sensitive and provides better practical results, but considering the costs and difficulties in interpretation (false positive and false negative results), its use remains confined to high-risk populations.

[Serologic verification of epidemic hemorrhagic fever during the lifting of the blockade in Sarajevo]. / Seroloska potvrda epidemije hemoragicne groznice u toku deblokade Sarajeva.

OBJECTIVES: After four years of Sarajevo siege, the deblocade started on July 1995. Many soldiers involved in the deblocade developed a clinical symptoms of hemorrhagic fever indicating a possible epidemic. METHODS: Suspected patients were treated in the war hospital Igman-Fojnica. Blood samples of all the patients were processed on IgM and IgG antibodies with ELISA test, using "the double sandwich" technique. RESULTS: IgM and IgG were performed on Puumala (PVV), Hantaan (HTN) and Dobrava antigens. 38 out of 45 treated serums had high antibody titres. Sera of 28 patients had high titres of specific IgM antibodies on Hantaan antigen (12,800). A ten patients had a same titre level for specific antibodies of Puumala antigen. A 20 patients had specific IgG antibodies on Dobrava antigen with the titre 400. Our results confirmed the epidemic for which were responsible two serotypes of HFRS-PVV and HTN. They also proved the existence of a new serotypes appearing for the first time in Sarajevo region. This epidemic confirms that BiH especially Sarajevo region are among the biggest epidemic areas of HFRS in Europa.

[Evolution of laboratory technics in the detection of herpes simplex virus infections]. / Evolucija laboratorijskih tehnika za dokazivanje herpes simplex virusnih infekcija.

In this report we proved that all of three methods for laboratory diagnosis of HSV infections which we used, have approximately the same degree of sensibility. Even though there is no statistically significant differences among sensibility of chosen methods, we think that IF test by monoclonal antibodies is the most suitable method for the routine work, in consideration of the high sensibility, typical specificity and fast results.