[Use of the passive hemagglutination inhibition reaction for the purpose of determining the antigenic activity of anatoxins in vitro]. / Ispol'zovanie reaktsii tormozheniia passivnoi gemaggliutinatsii s tsel'iu opredeleniia antigennoi aktivnosti anatoksinov in vitro.

The work deals with the study of the possibility of using the passive hemagglutination inhibition test (antibody neutralization) for the determination of the antigenic activity of botulinum toxoids, types A, B and E. Erythrocytic diagnostic preparations were shown to allow the determination of up to 0.1 g of antigen. At the same time in vitro determinations were found to satisfactorily correlate with the results of in vivo determinations of the antigenic activity of these toxoids in the antitoxin-fixation test.

[Evaluation of the quality of dry anatoxins in the process of their production]. / Otsenka kachestva sukhikh anatoksinov v protsesse ikh proizvodstva.

On the example of production of botulin toxoids of A, B and E types the authors demon strated the expediency of using the agar gel diffuse precipitation test for preliminary assessment of the toxoid activity, instead of a more expensive and complicated antitoxin-binding test.