ABSTRACT
BACKGROUND AND AIMS: Transcatheter pulmonary valve implantation (TPVI) is indicated to treat right-ventricular outflow tract (RVOT) dysfunction related to congenital heart disease (CHD). Outcomes of TPVI with the SAPIEN 3 valve that are insufficiently documented were investigated in the EUROPULMS3 registry of SAPIEN 3-TPVI. METHODS: Patient-related, procedural, and follow-up outcome data were retrospectively assessed in this observational cohort from 35 centres in 15 countries. RESULTS: Data for 840 consecutive patients treated in 2014-2021 at a median age of 29.2 (19.0-41.6) years were obtained. The most common diagnosis was conotruncal defect (70.5%), with a native or patched RVOT in 50.7% of all patients. Valve sizes were 20, 23, 26, and 29â mm in 0.4%, 25.5%, 32.1%, and 42.0% of patients, respectively. Valve implantation was successful in 98.5% [95% confidence interval (CI), 97.4%-99.2%] of patients. Median follow-up was 20.3 (7.1-38.4) months. Eight patients experienced infective endocarditis; 11 required pulmonary valve replacement, with a lower incidence for larger valves (P = .009), and four experienced pulmonary valve thrombosis, including one who died and three who recovered with anticoagulation. Cumulative incidences (95%CI) 1, 3, and 6 years after TPVI were as follows: infective endocarditis, 0.5% (0.0%-1.0%), 0.9% (0.2%-1.6%), and 3.8% (0.0%-8.4%); pulmonary valve replacement, 0.4% (0.0%-0.8%), 1.3% (0.2%-2.4%), and 8.0% (1.2%-14.8%); and pulmonary valve thrombosis, 0.4% (0.0%-0.9%), 0.7% (0.0%-1.3%), and 0.7% (0.0%-1.3%), respectively. CONCLUSIONS: Outcomes of SAPIEN 3 TPVI were favourable in patients with CHD, half of whom had native or patched RVOTs.
Subject(s)
Endocarditis, Bacterial , Endocarditis , Heart Defects, Congenital , Heart Valve Prosthesis Implantation , Heart Valve Prosthesis , Pulmonary Valve Insufficiency , Pulmonary Valve , Thrombosis , Adult , Humans , Cardiac Catheterization/adverse effects , Endocarditis/epidemiology , Endocarditis, Bacterial/complications , Heart Defects, Congenital/complications , Heart Valve Prosthesis/adverse effects , Heart Valve Prosthesis Implantation/adverse effects , Prosthesis Design , Pulmonary Valve/surgery , Pulmonary Valve Insufficiency/epidemiology , Pulmonary Valve Insufficiency/surgery , Registries , Retrospective Studies , Thrombosis/etiology , Treatment OutcomeABSTRACT
Coronary artery fistulas have been described in patients after heart transplantation more often than in the normal population. We reviewed our centre's database between 2008 and 2020. Thirty patients had coronary angiography and 13 showed non-cameral coronary artery fistulas in their first coronary angiography. Distribution, degree and evolution of the fistulas and characteristics of transplant procedure, patient and immunosuppressive treatments were analysed.
Subject(s)
Coronary Artery Disease , Coronary Vessel Anomalies , Fistula , Heart Transplantation , Child , Coronary Angiography , Coronary Artery Disease/diagnosis , Coronary Artery Disease/etiology , Coronary Vessel Anomalies/diagnostic imaging , Heart Transplantation/adverse effects , HumansABSTRACT
Percutaneous closure of atrial septal defect is recognised as a safe and effective procedure, however, in some patients complications may occur. Although chest pain has been sporadically reported, its exact aetiology has been poorly studied. Herein, a 14-year-old female with an atypical and long-lasting chest pain after percutaneous atrial septal defect closure is described.
Subject(s)
Heart Septal Defects, Atrial , Septal Occluder Device , Adolescent , Cardiac Catheterization/adverse effects , Chest Pain/diagnosis , Chest Pain/etiology , Female , Heart Septal Defects, Atrial/diagnosis , Heart Septal Defects, Atrial/surgery , Humans , Septal Occluder Device/adverse effects , Treatment OutcomeABSTRACT
A 4-year-old child of 10 kg weight, with four previous sternotomies, presented a severe right heart failure, due to a severe regurgitation of his bioprosthetic tricuspid valve. A percutaneous tricuspid valve in valve procedure with an Edwards S3 valve was offered for compassionate use, and performed, with no complications, and significant clinical condition improvement.
Subject(s)
Bioprosthesis , Heart Valve Prosthesis Implantation , Heart Valve Prosthesis , Tricuspid Valve Insufficiency , Bioprosthesis/adverse effects , Cardiac Catheterization , Child, Preschool , Heart Valve Prosthesis/adverse effects , Humans , Prosthesis Design , Prosthesis Failure , Treatment Outcome , Tricuspid Valve/diagnostic imaging , Tricuspid Valve/surgery , Tricuspid Valve Insufficiency/diagnosis , Tricuspid Valve Insufficiency/surgeryABSTRACT
No disponible
Subject(s)
Humans , Male , Female , Infant, Newborn , Ductus Arteriosus/surgery , Heart Defects, Congenital/surgery , Stents , Heart-Assist Devices , Retrospective Studies , Treatment OutcomeABSTRACT
No disponible
Subject(s)
Humans , Male , Infant, Newborn , Infant , Palliative Care/methods , Scimitar Syndrome/therapy , Scimitar Syndrome/diagnosisABSTRACT
No disponible
Subject(s)
Humans , Male , Infant, Newborn , Arterial Occlusive Diseases/surgery , Stenosis, Pulmonary Artery/surgery , Stents , Arterial Occlusive Diseases/diagnosis , Pulmonary Atresia/complications , Cardiac Catheterization/methodsABSTRACT
We implanted two sinus Superflex DS© stents in a systemic non-stenotic arterial duct of a newborn with hypoplastic left heart syndrome. Forty-eight hours later an important collapse of the stent was detected and treated with a balloon expandable stent. Sinus Superflex DS© has been specifically designed for systemic ducts. This complication generates doubts about its radial force in this scenario.
Subject(s)
Ductus Arteriosus/surgery , Hypoplastic Left Heart Syndrome/surgery , Prosthesis Failure , Stents/adverse effects , Angiography , Cardiac Surgical Procedures/instrumentation , Humans , Infant, Newborn , Male , Pulmonary Artery/surgery , Treatment OutcomeABSTRACT
No disponible
Subject(s)
Humans , Female , Child , Ductus Arteriosus, Patent/surgery , Heart Septal Defects, Atrial/surgery , Hypersensitivity/immunology , Nickel/adverse effects , Nickel/immunologyABSTRACT
We report an asymptomatic 5-year-old boy with coronary artery fistulas to pulmonary parenchyma and to systemic thoracic arteries, like a "natural bypass", detected during a coronary angiography performed 11 months after his heart transplant. One year later, a new coronary angiography showed no fistula. Some changes to immunosuppressive therapy during this time could be related to this evolution.
Subject(s)
Coronary Artery Disease/etiology , Everolimus/adverse effects , Fistula/etiology , Immunosuppressive Agents/adverse effects , Child, Preschool , Coronary Angiography , Coronary Artery Disease/diagnostic imaging , Fistula/diagnostic imaging , Heart Transplantation , Humans , MaleSubject(s)
Palliative Care/methods , Scimitar Syndrome/therapy , Humans , Infant , Infant, Newborn , Male , Scimitar Syndrome/diagnosisABSTRACT
"Persistence of the fifth aortic arch" is a rare congenital cardiovascular anomaly that consists of an abnormal vessel arising from the distal ascending aorta connecting with the systemic or pulmonary circulation. We report a case of a type A interruption of the aortic arch and a coarctation of the fifth aortic arch, which connected the ascending with the descending aorta. No cardiac surgery was required because a covered stent was successfully implanted in the fifth aortic arch when the patient was 4 years old. A chromosome 9 q arm duplication of uncertain significance was also found, an anomaly never described before in this clinical context.
