[Quantitative morphology of periferal erythrocytes and bone marrow erythrokaryocytes in acute leukemia and hemopoietic depressions]. / Kolichestvennaia morfologiia éritritsitov perifericheskoi krovi i éritrokariotsitov kostnogo mozga pri ostrykh leikozakh i depressiiakh krovetvoreniia.

Morphology of peripheral blood erythrocytes was studied in patients with acute leukemia and aplastic anemia by a Russian cytoanalyzer Mekos-C. Twenty-eight patients with acute myeloblastic leukemia, 15 with acute lymphoblastic leukemia, and 11 with aplastic anemia were examined. Erythrocytes (n = 500) were examined in fixed non-stained blood smears. Hemoglobin content and morphometric parameters of each cell were studied and automatic classification of cells was carried out. The data of computer morphodensitometry are compatible with the data of cytochemical studies of the bone marrow erythroid cells (PAS reaction after McManus). The results indicate circulation of erythrocyte subpopulations differing by shape and other signs (hemoglobin content, section area, shape factor) in the blood of patients with acute leukemia and aplastic anemia. The share of pathological erythrocytes in the peripheral blood reflects failure of erythropoiesis.

[Analysis of erythrocytes in the MEKOS-C system]. / Analiz éritrotsitov v sisteme "MEKOS-Ts".

Quantitative cytofluorimetric analysis of red cells by the MEKOS-C device provides complete information about peripheral blood erythrocytes, which cannot be obtained by other methods and equipment. An analysis is cheap and sensitive, this recommending it for practical hematology, toxicology, and narcology. The MEKOS-C device permits the preclinical diagnosis of a number of diseases and monitoring their treatment. The device is cheap and available for therapeutic and diagnostic institutions of all levels.