ABSTRACT
Analysis of the results of infusion hemodilution and traditional restitution of surgical blood less in 32 children subjected to urological surgery showed that hemodilution is associated with an increase of cardiac output and a reduction of the peripheral vascular resistance. Despite an increase of the volume of blood loss in hemodilution, the parameters of oxygen transport remain the optimal in the course of operation and the immediate postoperative period, an increased level of inorganic phosphates being conducive to maintenance of adequate oxygen metabolism. The authors claim that under conditions of infusion hemodilution donor blood preparations should not be transfused to children with surgical blood loss of up to 20%.
Subject(s)
Female Urogenital Diseases/surgery , Hemodilution , Hemodynamics , Male Urogenital Diseases , Oxygen/metabolism , Blood Loss, Surgical , Child , Child, Preschool , Humans , Oxygen/blood , Postoperative Period , Pulmonary Gas Exchange , Time FactorsSubject(s)
Bronchial Diseases/physiopathology , Hemodynamics , Lung Diseases/physiopathology , Pulmonary Gas Exchange , Adolescent , Bronchial Diseases/surgery , Child , Child, Preschool , Chronic Disease , Humans , Lung Diseases/surgery , Monitoring, Intraoperative , Postoperative Period , Preanesthetic MedicationABSTRACT
The blood coagulation system and fibrinolysis were studied in 16 children with chronic bronchopulmonary diseases, aged from 4 to 15 years, before surgery, immediately, and on the first day after the operation. The method of infusion hemodilution, under the control of hematocrit, hemoglobin and total protein, was used for the treatment of operation hemorrhage. The investigations conducted have revealed hypercoagulation signs in the patients before the beginning of the operation (as compared to normal children). Operative intervention has intensified many signs of hypercoagulation, however, in the postoperative period no clinical signs of hypercoagulation were observed in all the cases, that was associated with the positive effect of hemodilution.
Subject(s)
Anticoagulants/administration & dosage , Blood Coagulation/drug effects , Bronchial Diseases/surgery , Dextrans/administration & dosage , Hemodilution/methods , Lung Diseases/surgery , Postoperative Complications/prevention & control , Thrombosis/prevention & control , Adolescent , Blood Coagulation/physiology , Bronchial Diseases/blood , Child , Child, Preschool , Humans , Intraoperative Care , Lung Diseases/bloodABSTRACT
The effect of infusion hemodilution on hemodynamic parameters and oxygen-transport homeostasis was studied during elective chest surgery in 18 children with chronic bronchopulmonary diseases. The data obtained have evidenced the expediency of using the method of infusion hemodilution in children for the operative hemorrhage therapy, ensuring the adequate hemodynamics and oxygen-transport supply at all the operation stages and in the early postoperative period.
