ABSTRACT
An evaluation of production orders for medicated feedingstuffs for pigs given in 1998 in Schleswig-Holstein showed macrolides, lincomycin and tiamulin as frequently used antibiotical ingredients. The presented study analyses the production orders which include macrolides, lincomycin or tiamulin in more detail. There were large deviations to the rules of good clinical practise for the use of antibiotics (2000). The applied dosage was often lower than suggested in the literature.
Subject(s)
Animal Feed/statistics & numerical data , Anti-Bacterial Agents/administration & dosage , Diterpenes/administration & dosage , Lincomycin/administration & dosage , Macrolides/administration & dosage , Swine Diseases/prevention & control , Animal Feed/standards , Animals , Body Weight/physiology , Dose-Response Relationship, Drug , Germany , Retrospective Studies , SwineABSTRACT
An evaluation of production orders for medicated feedingstuffs for pigs given in 1998 in Schleswig-Holstein showed sulphonamides and combinations of sulphonamides and trimethoprim as frequently used antibiotical ingredients. The presented study analyses the production orders which include sulphonamides and combinations of sulphonamides and trimethoprim in more detail. There were large deviations to the rules of good clinical practise for the use of antibiotics. The applied dosage was often lower than suggested in the literature.
Subject(s)
Animal Feed/statistics & numerical data , Anti-Bacterial Agents , Anti-Infective Agents/administration & dosage , Drug Therapy, Combination/administration & dosage , Sulfonamides/administration & dosage , Swine Diseases/prevention & control , Trimethoprim/administration & dosage , Animal Feed/standards , Animals , Anti-Infective Agents/therapeutic use , Body Weight/physiology , Dose-Response Relationship, Drug , Drug Therapy, Combination/therapeutic use , Germany , Retrospective Studies , Sulfonamides/therapeutic use , Swine , Swine Diseases/drug therapy , Trimethoprim/therapeutic use , Trimethoprim, Sulfamethoxazole Drug Combination/administration & dosage , Trimethoprim, Sulfamethoxazole Drug Combination/therapeutic useABSTRACT
An evaluation of production orders for medicated feedingstuffs for pigs given in 1998 in Schleswig-Holstein showed aminoglycosides, colistin and beta-lactam antibiotics as regularly used antibiotical ingredients. The presented study analyses the production orders which include these antibiotics more in detail particularly with regard to the prescribed dosages. In part, there were deviations to the rules of good clinical practise for the use of anitbiotics. The applied dosage of spectinomycin and apramycin was often lower than suggested in the literature. The low oral bioavailability of amoxicillin was not considered when using amoxicillin in medicated feedingstuffs.
