Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 148
Filter
1.
Toxicol Sci ; 152(1): 10-6, 2016 07.
Article in English | MEDLINE | ID: mdl-27208075

ABSTRACT

The Evidence-based Toxicology Collaboration hosted a workshop on "The Emergence of Systematic Review and Related Evidence-based Approaches in Toxicology," on November 21, 2014 in Baltimore, Maryland. The workshop featured speakers from agencies and organizations applying systematic review approaches to questions in toxicology, speakers with experience in conducting systematic reviews in medicine and healthcare, and stakeholders in industry, government, academia, and non-governmental organizations. Based on the workshop presentations and discussion, here we address the state of systematic review methods in toxicology, historical antecedents in both medicine and toxicology, challenges to the translation of systematic review from medicine to toxicology, and thoughts on the way forward. We conclude with a recommendation that as various agencies and organizations adapt systematic review methods, they continue to work together to ensure that there is a harmonized process for how the basic elements of systematic review methods are applied in toxicology.


Subject(s)
Biomedical Research , Systematic Reviews as Topic , Toxicology , Animals , Humans , Biomedical Research/methods , Biomedical Research/standards , Consensus , Guidelines as Topic , Toxicology/methods , Toxicology/standards
18.
ALTEX ; 30(1): 74-103, 2013.
Article in English | MEDLINE | ID: mdl-23338808

ABSTRACT

The Evidence-based Toxicology Collaboration (EBTC) was established recently to translate evidence-based approaches from medicine and health care to toxicology in an organized and sustained effort. The EBTC held a workshop on "Evidence-based Toxicology for the 21st Century: Opportunities and Challenges" in Research Triangle Park, North Carolina, USA on January 24-25, 2012. The presentations largely reflected two EBTC priorities: to apply evidence-based methods to assessing the performance of emerging pathway-based testing methods consistent with the 2007 National Research Council report on "Toxicity Testing in the 21st Century" as well as to adopt a governance structure and work processes to move that effort forward. The workshop served to clarify evidence-based approaches and to provide food for thought on substantive and administrative activities for the EBTC. Priority activities include conducting pilot studies to demonstrate the value of evidence-based approaches to toxicology, as well as conducting educational outreach on these approaches.


Subject(s)
Toxicology/methods , Toxicology/standards , Animals , Biomarkers , High-Throughput Screening Assays , Humans , Reproducibility of Results , Toxicology/legislation & jurisprudence , United States , United States Food and Drug Administration
SELECTION OF CITATIONS
SEARCH DETAIL
...