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J Neuropsychiatry Clin Neurosci ; 29(2): 119-127, 2017.
Article in English | MEDLINE | ID: mdl-27899053

ABSTRACT

The authors explored the relations between clinical/demographic characteristics and performance on a neuropsychological battery (eight tests) in a cohort (N=46) of multiple sclerosis (MS) subjects. Findings resulted from a secondary analysis of a study examining the relationships between imaging biomarkers in MS and cognitive tasks of executive functioning. The objective was to determine whether the overlapping test results could be judiciously combined and associated with clinical/demographic variables. Canonical-correlation analysis (CCA) was utilized, and it was found that differences between performance on untimed tests, and the sum of performance on timed Trail-Making Tests, Parts A and B, best matched clinical/demographic variables, and gender was the most important feature.


Subject(s)
Cognition Disorders/etiology , Multiple Sclerosis/complications , Sex Characteristics , Statistics as Topic/methods , Adult , Cognition Disorders/diagnostic imaging , Cohort Studies , Executive Function/physiology , Female , Humans , Male , Middle Aged , Multiple Sclerosis/diagnostic imaging , Neuropsychological Tests , Young Adult
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