Aberrant Location of Low-grade Myofibroblastic Sarcoma of the Gingiva in Posterior Maxilla.

Low-grade myofibroblastic sarcoma is a malignant tumor arising from myofibroblasts, which has only recently become clearly defined. It represents a rare entity developing in the soft tissues of the head and neck. About 20 cases have been reported in the oral cavity, especially in the tongue and bone, while gingiva as the primary site has been described only twice to date. Diagnostic methods include histology and immunohistochemistry. The present report concerns a case of a 13-year-old female child who presented with gingival nonulcerated swelling that was interpreted for a long time as a gingival fibroma. A low-grade myofibroblastic sarcoma was diagnosed and the patient underwent a segmental osteotomy of the right posterior region of the maxilla. There was no sign of recurrence or metastatic disease during the 12-month postoperative period. HOW TO CITE THIS ARTICLE: Padmawar NS, Bhadange S, Mustilwar RG, et al. Aberrant Location of Low-grade Myofibroblastic Sarcoma of the Gingiva in Posterior Maxilla. Int J Clin Pediatr Dent 2021;14(6):816-819.

Assessment of Correlation of Growth Hormone Receptor Gene with Tooth Dimensions: A CBCT and Genotyping Study.

AIM: Assessment of root morphology, size, and amount of bone around tooth is essential before starting the orthodontic treatment. The present study aimed to assess the relationship between tooth dimensions with two gene variants of growth hormone (GH), namely rs6184 and rs6180. MATERIALS AND METHODS: This study was conducted on 218 subjects (males: 104, females: 114) requiring orthodontic treatment. All underwent cone beam computed tomography (CBCT) scan for orthodontic treatment planning with Kodak CBCT machine. In all teeth, crown height (CH), root length (RL), and crown-root ratio were evaluated. Two growth hormone receptor (GHR) variants (rs6184 and rs6180) were genotyped using the TaqMan genotyping assay. RESULTS: The mean CH and RL of all teeth, that is, maxillary and mandibular central incisors, lateral incisor, canine, first premolar, second premolar, first molar, and second molar, were measured. There was no significant difference in males and females (P > 0.05). Allele frequencies of GHR variants for rs6180 and rs6184 were 48.1% and 8.92%, respectively. Multiple regression analysis showed GHR rs6184 association with maxillary central incisor CH, maxillary canine RL, mandibular canine CH, and mandibular first premolar RL (P < 0.05). CONCLUSION: There was correlation of CH of maxillary and mandibular canine and RL of maxillary canine and mandibular first premolar with GHR rs6184.