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1.
Saudi J Anaesth ; 11(4): 449-453, 2017.
Article in English | MEDLINE | ID: mdl-29033727

ABSTRACT

BACKGROUND: Ultrasound-guided caudal block injection is a simple, safe, and effective method of anesthesia/analgesia in pediatric patients. The volume of caudal drug required has always been a matter of debate. MATERIALS AND METHODS: This present prospective, randomized, double-blinded study aimed to measure extent of the cranial spread of caudally administered levobupivacaine in Indian children by means of real-time ultrasonography. Ninety American Society of Anesthesiologists I/II children scheduled for urogenital surgeries were enrolled in this trial. Anesthesia and caudal analgesia were administered in a standardized manner in the patients. The patients received 0.5 ml/kg or 1 ml/kg or 1.25 ml/kg of 0.125% levobupivacaine according to the group allocated. Cranial spread of local anesthetic was noted using ultrasound. RESULTS: There was no difference in the spread when related to age, sex, weight, or body mass index. A significant difference of ultrasound-assessed cranial spread of the local anesthetic was found between Group 1 (0.5 ml/kg) with both Group 2 (1 ml/kg) (P = 0.001) and with Group 3 (1.125 ml/kg) (P < 0.001) but there is no significant difference between Group 2 and Group 3 (P = 0.451) revealing that spinal level spread is only different between 0.5 ml/kg and 1 ml/kg of local anesthetic. CONCLUSION: In conclusion, the ultrasound assessment of local anesthetic spread after a caudal block showed that cranial spread of the block is dependent on the volume injected into the caudal space. Since there was no difference between 1 ml/kg and 1.25 ml/kg, to achieve a dermatomal blockade up to thoracic level, we might have to increase the dose beyond 1.25 ml/kg, keeping the toxic dose in mind.

3.
Kathmandu Univ Med J (KUMJ) ; 17(58): 179-181, 2017.
Article in English | MEDLINE | ID: mdl-34547853

ABSTRACT

Pierre Robin Syndrome is a well-known difficult airway condition. We present a case of successful management of a neonate in severe respiratory distress with diagnosed Pierre Robin syndrome, pneumonitis and in impending respiratory failure. We wish to highlight a sequence of measures instituted for the child including use of a supraglottic device Igel for immediate airway rescue when intubation was nearly impossible and mask ventilation very difficult. We sutured patient's tongue with his lip near the chin to keep the upper airway patent as an intermediate intervention and we could subsequently successfully treat the concomitant lung infection. Child could be discharged from hospital alive and healthy.

4.
Nepal Med Coll J ; 10(1): 16-9, 2008 Mar.
Article in English | MEDLINE | ID: mdl-18700624

ABSTRACT

The present study compared the efficacy of preloading with colloid "Haemaccel" with vasoconstrictor (intravenous ephedrine sulphate) in preventing hypotension during propofol induction. This prospective, randomized study included 120 patients of Amercan Society of Anaesthesiologists (ASA) physical status I and II ageing 21 to 50 years of both gender coming for routine surgery. Patients were randomly allocated into three groups with 40 patients in each. Group A (control) did not receive any study medication, group B received Haemaccel (10 ml/kg intravenously over 10-15 minutes) and group C received injection ephedrine (0.2 mg/kg iv) prior to induction of anaesthesia. Propofol (2.5 mg/kg iv) was used for induction of anaesthesia. Heart rate and blood pressure were recorded before induction (baseline) and then every minute for 5 minutes after administering propofol. Anaesthesia was continued with standard technique thereafter. Hypotension was defined as fall in systolic blood pressure more than 20% from the basal value. The incidence of hypotension in Haemaccel (23.1%) or ephedrine group (22.5%) was significantly less than the control group (67.5%, P<0.01). We conclude that though preloading with colloid (Haemaccel) or prior injection of sympathomimetic (ephedrine) are not fully efficacious in preventing hypotension caused by propofol induction, both decrease the incidence in significant number of patients with heart rate less than baseline value in the colloid group.


Subject(s)
Anesthesia , Anesthetics, Intravenous/adverse effects , Ephedrine/administration & dosage , Hypotension/prevention & control , Plasma Substitutes/administration & dosage , Polygeline/administration & dosage , Propofol/adverse effects , Vasoconstrictor Agents/administration & dosage , Adult , Female , Humans , Hypotension/chemically induced , Infusions, Intravenous , Injections, Intravenous , Male , Middle Aged
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