Synthesis and insecticidal activity of acridone derivatives to Aedes aegypti and Culex quinquefasciatus larvae and non-target aquatic species.

A serious Mosquito borne yellow fever is one of the grave diseases which affect the major population. Since there is no specific treatment for yellow fever, there is a necessity to develop an effective agent. The series of acridinone analogues 3 to 5 were synthesized with help of non-conventional microwave heating and confirmed by respective spectral characterization. 5c and 3b showed highest activity to kill 90% of larvae against A. aegypti and C. quinquefasciatus, respectively. Also the active products were treated to check the mortality of non-target aquatic species. Through the reports of the larvicidal bioassay, compounds 3b against C. quinquefasciatus whereas 5c against A. aegypti were found to be more active. By keeping this as a platform, further extension of the work can be done to find out a valuable drug for controlling disease vectors.

Acaricidal, insecticidal, and larvicidal efficacy of aqueous extract of Annona squamosa L peel as biomaterial for the reduction of palladium salts into nanoparticles.

In recent years the utilization of secondary metabolites from plant extract has emerged as a novel technology for the synthesis of various nanoparticles. In this paper we studied the potential of nanocrystalline palladium nanoparticles production using acaricidal, insecticidal and larvicidal efficacy of Annona squamosa L aqueous peel extract as the biomaterial for the first time. The synthesized nanoparticles were characterized and confirmed as palladium nanoparticles by using UV-visible spectroscopy, XRD and TEM analysis. The results clearly showed that the compounds containing -OH as a functional group played a critical role in capping the nanoparticles. Also the results highlight the possibility of green pathways to produce palladium nanoparticles.