Subject(s)
Amodiaquine/therapeutic use , Artemisinins/therapeutic use , Fever/etiology , Malaria/diagnosis , Plasmodium malariae/isolation & purification , Primaquine/therapeutic use , Travel , Adult , Antimalarials/therapeutic use , Drug Combinations , Humans , India , Kenya , Malaria/drug therapy , Malaria/parasitology , Male , Treatment OutcomeABSTRACT
Here we present a case of 55 year old male who presented with lower respiratory tract infection and clinical findings of systolic murmur at apex and hepatosplenomegaly and later on multiple cerebral emboli which on further evaluation turned out to be myeloproliferative neoplasm associated with cardiac mass with left ventricular mid-cavity obstruction.
Subject(s)
Cardiomyopathy, Hypertrophic/etiology , Intracranial Embolism/etiology , Primary Myelofibrosis/diagnosis , Humans , Male , Middle Aged , Primary Myelofibrosis/genetics , Splenomegaly/etiologyABSTRACT
Cervicofacial actinomycosis is today a rare disease in our country. Isolated neck swelling due to actinomycosis is extremely rare. A case of 52 year old man with an isolated neck swelling due to actinomycosis without any discharging sinus is reported here.
Subject(s)
Actinomycosis, Cervicofacial/pathology , Actinomycosis, Cervicofacial/diagnosis , Actinomycosis, Cervicofacial/drug therapy , Anti-Bacterial Agents/therapeutic use , Humans , Male , Middle Aged , Penicillins/therapeutic useABSTRACT
Disseminated histoplasmosis is a relentlessly progressive granulomatous disease which can mimic many other granulomatous diseases including tuberculosis. A 48-year-old male was referred to us with 11 months history of multiple subcutaneous swellings and ulcerations over the upper and lower limbs and fever for 2 months. He was evaluated outside for several months and received anti tubercular drugs for about 2 years in the past for a granulomatous infection of bone and soft tissue identified by various biopsies, without any improvement. When he was evaluated and fresh biopsies were taken, they were stained for fungus and disseminated histoplasmosis was detected. This case confirms the importance of considering fungal infections as a possibility while treating disseminated granulomatous infections, even in immune-competent patients, especially if response to treatment is inadequate.
ABSTRACT
Miller Fisher syndrome (MFS) is a variant of Guillan Barre syndrome characterized by the triad of ophthalmoplegia, ataxia and areflexia. Recurrences are exceptional with Miller Fisher syndrome. We are reporting a case with two episodes of MFS within two years. Initially he presented with partial ophthalmoplegia, ataxia. Second episode was characterized by full-blown presentation characterized by ataxia, areflexia and ophthalmoplegia. CSF analysis was typical during both episodes. Nerve conduction velocity study was fairly within normal limits. MRI of brain was within normal limits. He responded to symptomatic measures initially, then to steroids in the second episode. We are reporting the case due to its rarity.
Subject(s)
Miller Fisher Syndrome/diagnosis , Adult , Humans , Male , Methylprednisolone/therapeutic use , Miller Fisher Syndrome/drug therapy , Neuroprotective Agents/therapeutic use , RecurrenceABSTRACT
Primary adrenal insufficiency is an uncommon disease which has worldwide distribution. The commonest cause in underdeveloped countries is tuberculosis followed by autoimmune destruction of the adrenal gland. We report a case of a 15 years boy who had congenital adrenal insufficiency associated with achalasia of the cardia and deficient tear secretion.
