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1.
Brain Behav Immun ; 88: 1-5, 2020 08.
Article in English | MEDLINE | ID: mdl-32526447

ABSTRACT

'The Mask' has become a byword and a precious possession universally. Except for its use by the medical fraternity, answers to the common questions-whether it provides enough protection, which type is optimal for the general public and who really needs to don it, remain poorly understood. For a frontline healthcare worker, wearing mask is a necessity as an important person protection equipment, it is perhaps the most-powerful psychological symbol for the general public. Surprisingly, it even undermines all other recommended practices of infection control and breaking the transmission chain of Covid-19, like hand washing, personal hygiene and social distancing. 'The mask' has evolved with time and yet there is a need to further improve the design for safety, tolerability and comfort. In this review we present the journey of face mask, originating from the first masks aimed at stopping the bad smell to its industrial use to its all-important place in the medical field. Various types of face masks, their filtration efficiency, reusability and current recommendations for their use are presented.


Subject(s)
Coronavirus Infections/prevention & control , Masks , Pandemics/prevention & control , Pneumonia, Viral/prevention & control , Respiratory Protective Devices , Symbolism , Betacoronavirus , COVID-19 , Coronavirus Infections/transmission , Equipment Reuse , Guidelines as Topic , Humans , Infection Control , Pneumonia, Viral/transmission , SARS-CoV-2 , Textiles
2.
J Stroke Cerebrovasc Dis ; 27(6): 1539-1545, 2018 Jun.
Article in English | MEDLINE | ID: mdl-29422380

ABSTRACT

BACKGROUND: In acute ischemic stroke (AIS), treatment with intravenous tissue-type plasminogen activator (IV-tPA) is time-sensitive. All stroke centers make continual efforts to reduce door-to-needle time (DNT) with varying success. We present the impact of modifications to our stroke activation protocol on DNT. METHODS: We included 404 consecutive patients with AIS receiving IV-tPA between January 2014 and December 2016. First changes in stroke activation protocol were made in March 2015 in the form of prenotification by paramedics, direct transfer from ambulance to computed tomography (CT) scanner, and rapid en route neurological assessment by an emergency physician and neurologist. In March 2016, a second amendment was made where a stroke nurse accompanied the patient to expedite various steps in the treatment pathway, including endovascular treatment in eligible cases. RESULTS: Both protocol amendments resulted in improvement in DNT and door-to-CT time from 84 ± 47 minutes before intervention to 69 ± 33 minutes after protocol amendment 1 to 59 ± 37 minutes after protocol amendment 2. In particular, the second amendment (144 patients) showed significant shortening of DNT compared with the 137 patients before (59 ± 37 minutes versus 69 ± 33 minutes, P = .020), with a higher percentage achieving the target of 60 minutes (68.1% versus 48.2%, P < .001). This finding was attributed to a reduction in both door-to-CT time and CT-to-needle time. This improvement remained consistent over subsequent months. CONCLUSIONS: The application of a simple systems-based, multidisciplinary stroke activation protocol may help in significant reduction in DNT. Encouraging increased patient ownership by stroke nurses appeared to be a promising approach for timely administration of definitive acute therapies.


Subject(s)
Brain Ischemia/drug therapy , Delivery of Health Care, Integrated/organization & administration , Fibrinolytic Agents/administration & dosage , Stroke/drug therapy , Thrombolytic Therapy/methods , Time-to-Treatment/organization & administration , Tissue Plasminogen Activator/administration & dosage , Administration, Intravenous , Allied Health Personnel/organization & administration , Brain Ischemia/diagnosis , Brain Ischemia/physiopathology , Clinical Protocols , Emergency Service, Hospital/organization & administration , Fibrinolytic Agents/adverse effects , Humans , Neurologic Examination , Neurologists/organization & administration , Patient Care Team/organization & administration , Stroke/diagnosis , Stroke/physiopathology , Tertiary Care Centers , Thrombolytic Therapy/adverse effects , Time Factors , Tissue Plasminogen Activator/adverse effects , Tomography, X-Ray Computed , Treatment Outcome
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