ABSTRACT
Penile calcification was detected in 6 of 32 patients (19%) with end-stage renal disease (ESRD) using soft tissue x-ray techniques. Having been maintained on hemodialysis for a minimum of one year, all the affected patients showed clinical evidence of secondary hyperparathyroidism and calcification in the blood vessels of some other tissues. All had erectile impotence, while in 1 patient gangrene of the penis developed. Penile calcification is probably more common in ESRD patients than realized and should be looked for as a possible cause of impotence in male patients treated with maintenance hemodialysis.
Subject(s)
Calcinosis/etiology , Kidney Failure, Chronic/complications , Kidney Failure, Chronic/therapy , Penile Diseases/etiology , Renal Dialysis , Adult , Calcinosis/diagnostic imaging , Erectile Dysfunction/etiology , Humans , Hyperparathyroidism, Secondary/etiology , Male , Middle Aged , Penile Diseases/diagnostic imaging , Radiography , Time FactorsSubject(s)
Carcinoma, Squamous Cell/secondary , Lung Neoplasms/secondary , Osteoarthropathy, Secondary Hypertrophic/diagnostic imaging , Uterine Cervical Neoplasms , Adult , Carcinoma, Squamous Cell/diagnostic imaging , Carcinoma, Squamous Cell/pathology , Diagnosis, Differential , Female , Humans , Lung Neoplasms/diagnostic imaging , Lung Neoplasms/pathology , Radiography, ThoracicABSTRACT
Two-hundred paraplegic men were studied to determine the nature of their axial skeletal changes. Forty-two per cent had sacro-iliac (SI) joint changes which varied from marginal blurring, erosion, sclerosis, and narrowing of the joint space (9%) to complete obliteration of the joints (33%). Radiographs of the thoracolumbar spine revealed syndesmophytes (9%), interspinous ossification (2%), intervertebral disk calcification (1.5%), and large osteophytes (2%). These changes had no relation to race, age (except spine changes), or paralysis level, but were related to the duration of the paralysis. The observed skeletal changes mimic HLA-B27 arthropathy. However, the presence of para-osteoarthropathies and negative HLA-B27 in paraplegics would help in differential diagnosis.
Subject(s)
Paraplegia/diagnostic imaging , Pelvic Bones/diagnostic imaging , Sacroiliac Joint/diagnostic imaging , Spine/diagnostic imaging , Adult , Aged , HLA Antigens/analysis , Humans , Male , Middle Aged , Paraplegia/immunology , RadiographyABSTRACT
There are two types of hypertrophic osteoarthropathy; (a) the secondary type, by far the most common and usually associated with bronchogenic carcinoma; and (b) the idiopathic type, a rare disorder occurring predominantly in males and not associated with any known disease process. Both may be associated with peculiar skin changes known as pachyderma. When idiopathic hypertrophic osteoarthropathy (IHOA) is associated with pachyderma it is called pachydermoperiostosis. In extremely rare instances, IHOA may occur without pachyderma. Three such cases are described.
