Enhanced osseointegration of drug eluting nanotubular dental implants: An in vitro and in vivo study.

Faster and predictable osseointegration is crucial for the success of dental implants, especially in patients with compromised local or systemic conditions. Despite various surface modifications on the commercially available Titanium (Ti) dental implants, the bioactivity of Ti is still low. Thus, to achieve both biological and therapeutic activity on titanium surfaces, surface modification techniques such as titanium nanotubes have been studied as nanotube surfaces can hold therapeutic drugs and molecules. The main aim of the present research work is to study the early osseointegration around the novel Simvastatin drug eluting nanotubular dental implant. In the present research, the titanium nanotubes were fabricated on the screw-shaped dental implant surface and the Simvastatin drug was loaded into the nanotubes using the ultrasonication dip method. In vitro and In vivo studies were carried out on the modified dental implants. In vitro cell culture study reported enhanced osteogenic activity on the drug-loaded nanotube surface implants. The invivo animal studies were evaluated by micro-CT, histopathology, and reverse torque removal analysis methods. The test results showed faster osseointegration with the strong interface on the Simvastatin drug-loaded implant surface at 4 weeks of healing as compared to the control implants.

Progressive resistance training ameliorates deteriorating cardiac autonomic dysfunction, subclinical inflammation and endothelial dysfunction in type 2 diabetes mellitus: A randomized control trial.

BACKGROUND AND AIMS: To investigate the effect of resistance training (RT) on outcomes of cardiac autonomic control, biomarkers of subclinical inflammation, endothelial dysfunction, and angiotensin II in T2DM patients with CAN. METHODS: Fifty six T2DM patients with CAN were recruited in the present study.After baseline assessment of all outcome variables, patients were randomly allocated into two groups - RT (n = 28) and Control (n = 28). The experimental group underwent 12 weeks of RT and the control group received usual care. RT was performed at an intensity of 65%-75% of 1 RM, 3 times/week for 12 weeks. RT program included 10 exercises of major muscle groups in the body. Cardiac autonomic control parameters, subclinical inflammation and endothelial dysfunction biomarkers, and serum angiotensin II concentration were assessed at baseline and after 12 weeks. RESULTS: Parameters of cardiac autonomic control showed significant improvement after RT (p < 0.05). Interleukin-6, interleukin-18 were significantly reduced while endothelial nitric oxide synthase was significantly increased post-RT (p < 0.05). CONCLUSIONS: Findings of the present study suggest that RT has the potential to enhance deteriorating cardiac autonomic function in T2DM patients with CAN. RT also seems to have an anti-inflammatory role and it may also play some role in vascular remodeling in these patients. TRIAL REGISTRATION: CTRI/2018/04/013321, Registered prospectively on 13th April 2018, Clinical Trial Registry, India.

Physicochemical Properties of UV-Irradiated, Biaxially Oriented PLA Tubular Scaffolds.

PLA and its blends are the most extensively used materials for various biomedical applications such as scaffolds, implants, and other medical devices. The most extensively used method for tubular scaffold fabrication is by using the extrusion process. However, PLA scaffolds show limitations such as low mechanical strength as compared to metallic scaffolds and inferior bioactivities, limiting their clinical application. Thus, in order to improve the mechanical properties of tubular scaffolds, they were biaxially expanded, wherein the bioactivity can be improved by surface modifications using UV treatment. However, detailed studies are needed to study the effect of UV irradiation on the surface properties of biaxially expanded scaffolds. In this work, tubular scaffolds were fabricated using a novel single-step biaxial expansion process, and the surface properties of the tubular scaffolds after different durations of UV irradiation were evaluated. The results show that changes in the surface wettability of scaffolds were observed after 2 min of UV exposure, and wettability increased with the increased duration of UV exposure. FTIR and XPS results were in conjunction and showed the formation of oxygen-rich functional groups with the increased UV irradiation of the surface. AFM showed increased surface roughness with the increase in UV duration. However, it was observed that scaffold crystallinity first increased and then decreased with the UV exposure. This study provides a new and detailed insight into the surface modification of the PLA scaffolds using UV exposure.

Impact of resistance training on muscle fatigue in type 2 diabetes mellitus patients during dynamic fatigue protocol.

BACKGROUND: Type 2 diabetes mellitus (T2DM) is often accompanied with several neuromuscular complications of which muscle fatigue is one of the scantily studied and less-explored complication of this disease. OBJECTIVE: To investigate the effects of resistance training (RT) on muscle fatigue markers from electromyography (EMG) and capillary blood in T2DM patients. METHODS: Forty T2DM patients were randomized to either RT (n = 20) or control group (n = 20). They were assessed for EMG indices of muscle fatigue along with blood lactate (at three time points: Lactatepre, Lactatepeak, Lactatepost) during a dynamic fatigue protocol. Dynamic fatigue protocol consisted of 5 sets of leg press exercise at 10 repetition maximum intensity. RT group performed moderate intensity (65%-75% 1 repetition maximum) RT 3 times/week for 12 weeks. Control group followed usual routine. RESULTS: Findings revealed that EMG amplitude (root mean square) and Dimitrov's muscle fatigue index (FInsmk) decreased significantly while median frequency (MF) increased significantly during the dynamic fatigue protocol for both vastus medialis (Root mean square, p = .02; FInsmk, p = .001; MF, p < .001) and vastus lateralis muscle (Root mean square, p= .04,FInsmk,p = .01; MF, p < .001) post-RT. Blood lactate responses did not change after RT (Lactatepre, p = .55; Lactatepeak, p = .91; Lactatepost, p = .33). CONCLUSIONS: Findings of the present study illustrated that moderate intensity RT led to a significant reduction muscle fatigue in knee extensor muscles of T2DM patients. These results reinforce the utilization of RT in patients with T2DM.

Muscle activation patterns around knee following neuromuscular training in patients with knee osteoarthritis: secondary analysis of a randomized clinical trial.

OBJECTIVE: To compare the effects of neuromuscular training (NMT) to a quadriceps strength training (QT) program on co-contraction index (CCI) of knee muscles in patients with knee osteoarthritis (OA). METHODS: Sixty-six knee OA patients with varus malalignment were recruited from the physiotherapy outpatient department of the university. After baseline measurements, they were randomly assigned into two groups: NMT (n = 33) and QT (n = 33). Patients in NMT group received neuromuscular exercises whereas QT group received conventional strengthening exercises for a period of 12 weeks, three times per week. Electromyographic (EMG) activity of quadriceps, hamstring and gastrocnemius muscle was evaluated during treadmill walking before and after 12 weeks of intervention period and CCI of medial quadriceps-medial hamstring (med QH), lateral quadriceps-lateral hamstring (lat QH), medial quadriceps-medial gastrocnemius (med QG) and, lateral quadriceps and lateral gastrocnemius (lat QG) was calculated. RESULTS: There was a significantly greater reduction in CCI of med QH (p = 0.02) and lat QH (p = 0.01) in the NMT group than the QT group. Whereas both NMT and QT led to statistically similar reductions in CCI of med QG (p = 0.08) and lat QG (p = 0.66). CONCLUSION: Findings of this study suggest that NMT led to a greater reduction in CCI of knee muscles than QT which indicates that enhanced sensori-motor control attained by NMT could reduce knee loading in knee OA patients with varus malalignment.

Leisure-Time Physical Activity and Glycemic Control Independently Predicts Cardiac Autonomic Neuropathy in Type 2 Diabetes Mellitus.

BACKGROUND: Though cardiac autonomic neuropathy (CAN) is a common complication of type 2 diabetes mellitus (T2DM); still, there is lack of clarity on pathophysiological correlates for its onset and progression. Therefore, the purpose of this study was to investigate the predictive ability of lifestyle and cardiometabolic risk factors for CAN in T2DM patients. METHODS: A total of 105 Indian T2DM patients were recruited in the present study. Cardiometabolic risk factors, such as glycemic control, lipids, resting heart rate, systolic and diastolic blood pressure, and lifestyle risk parameters, such as physical activity levels and sleep quality were assessed. Standard cardiovascular autonomic reflex tests were performed for diagnosing CAN by Ewing's criteria. RESULTS: Leisure-time physical activity and glycosylated hemoglobin were significant independent predictors of CAN in T2DM. Leisure-time physical activity and glycosylated hemoglobin predicted the occurrence of CAN at cutoff values ≤4.68 metabolic equivalent-hours per week (P = .007) and >7.5% (P = .002), respectively. CONCLUSIONS: The T2DM patients should be encouraged to engage in leisure-time physical activity of at least 4.68 metabolic equivalent-hours per week (equivalent to 1.2 h of walk or 0.6 h of jog per week) and therapeutic strategies for controlling hyperglycemia in T2DM should aim to reduce glycosylated hemoglobin below 7.5% to reduce CAN occurrence.

Type 2 Diabetes Mellitus Patients Manifest Greater Muscle Fatigability Than Healthy Individuals During Dynamic Fatigue Protocol.

OBJECTIVE: The present study aimed to investigate the electromyographic (EMG) indices of muscle fatigue along with biochemical marker of fatigue-that is, blood lactate-during a dynamic fatigue protocol in individuals with type 2 diabetes mellitus (T2DM) vs a healthy control group. Secondarily, it aimed to examine the association between EMG indices of muscle fatigue and blood lactate in these patients. METHODS: Thirty-four participants took part in the study: 19 individuals with T2DM (age, 53.5 ± 6.85 years) and 15 age-matched healthy controls (age, 50.2 ± 3.55 years). Participants performed a dynamic fatigue protocol consisting of 5 sets of 10 repetitions each at an intensity of the 10-repetition maximum. Surface EMG of the vastus medialis and vastus lateralis muscles was recorded during the dynamic fatigue protocol, and EMG indices such as median frequency (MF), slope of MF (MFslope), Dimitrov muscle fatigue spectral index, and root-mean-square were evaluated for each contraction across all the 5 sets. Blood lactate concentrations were also assessed 3 times during the fatigue protocol. RESULTS: Findings revealed that EMG muscle fatigue indices such as MF, MFslope, and Dimitrov muscle fatigue spectral index were significantly altered in individuals with T2DM vs healthy individuals across the sets and repetitions for both the vastus medialis (P < .001) and vastus lateralis muscles (P < .001). There was a significantly greater rise in blood lactate in individuals with T2DM than in healthy individuals (P < .001), which was not found to be associated with changes in EMG indices of muscle fatigue. CONCLUSION: Findings suggest the existence of significantly greater fatigue in the knee extensor muscles of individuals with T2DM than healthy individuals.

Electromyographic Activity of Hip Musculature During Functional Exercises in Participants With and Without Chronic Ankle Instability.

OBJECTIVE: The main objective of the present study was to investigate the electromyographic (EMG) activity of gluteus medius (Gmed) and gluteus maximus (Gmax) muscles during functional exercises in subjects with chronic ankle instability (CAI) vs healthy controls. METHODS: Seventeen subjects (age, 24.4 ± 2.03 years) with CAI and 17 healthy controls (age, 24.6 ± 2.57 years) were recruited for the present study. For all participants, after testing maximum voluntary isometric contraction of the Gmed and Gmax muscle, EMG activity of these muscles was recorded during functional exercises, such as the Y Balance Test and the single-leg squat with and without Swiss ball. RESULTS: EMG activity of Gmed and Gmax was found to be significantly (P < .05) reduced during all functional exercises in subjects with CAI when compared with healthy controls. No significant differences (P > .05) were observed in the EMG activity of both muscles across different functional exercises. CONCLUSION: Our findings indicate that EMG activity of hip muscles is significantly reduced in CAI subjects, which might give an indication regarding the inclusion of hip muscle strengthening (Gmax and Gmed) in the rehabilitation of CAI. Moreover, Gmed and Gmax muscle activity did not vary during the different functional exercises within each group, which might indicate that activation pattern of these muscles are not sensitive to the type of functional task.

Biocompatibility analysis of PLA based candidate materials for cardiovascular stents in a rat subcutaneous implant model.

Modification of Polylactic acid (PLA), a biopolymer, is a strategy still to be fully explored for the next generation of bioresorbable vascular stent (BVS) biomaterials. With this focus, inclusions upto 5% of Polycaprolactone (PCL) and Magnesium in PLA were tested in the rat subcutaneous model and their cellular and tissue interactions characterized, specifically with respect to inflammatory response, angiogenesis and capsularization. The cytokines IL6, TNF Alpha and IL-1Beta were estimated in the peri-implant tissue, all of which showed a non-significant difference between the non-implanted animals and those containing PLA by 8 weeks, speaking to the benign nature of PLA as an implant biomaterial. Both modified materials, had increased macrophage counts and cytokine levels, except IL6 at 8 weeks. Vascularization only at 8 weeks in PLA PCL containing tissue was significantly higher than pure PLA, which may be more carefully controlled along with the material hydrophobicity for possible efforts towards therapeutic angiogenesis. Capsule thickness, measured by staining with both Hematoxylin & Eosin and Masson's Trichome did not show any differences between materials, including PLA.

Influence of Forward Head Posture on Cervicocephalic Kinesthesia and Electromyographic Activity of Neck Musculature in Asymptomatic Individuals.

OBJECTIVE: The purpose of this study was to compare cervicocephalic kinesthesia and electromyographic (EMG) activity of neck muscles-upper trapezius (UT) and sternocleidomastoid (SCM)-between individuals with and without forward head posture (FHP) and to examine the correlation between cervicocephalic kinesthesia and craniovertebral angle (CVA). METHODS: Twenty-two asymptomatic individuals with FHP and 22 without FHP were recruited for the present study. Craniovertebral angle was measured, and those with CVA ≤53° were assigned to the FHP group, whereas those with CVA >53° were assigned to the control group. Thereafter, cervicocephalic kinesthesia and EMG activity of the neck muscles were assessed. Cervicocephalic kinesthesia was measured using a head repositioning accuracy test for all cervical spine motions. EMG activity of the UT and SCM muscles was recorded at rest and during activity. RESULTS: Position-sense error values were found to be significantly greater for all directions-ie, flexion, extension, side flexion, and rotation-in participants with FHP than those without (P < .05). EMG activity of the UT and SCM muscles was found to be significantly raised both at rest and during activity in individuals with FHP relative to the non-FHP group (P < .05). Position-sense error values showed a significant inverse correlation with CVA (P < .05). CONCLUSION: Findings of the present study suggest that cervicocephalic kinesthesia and activation patterns of the neck muscles may be significantly altered in individuals with FHP. Also, cervicocephalic kinesthesia is significantly associated with the severity of FHP.

Diagnostic Validity of Cardiopulmonary Exercise Testing for Screening Pulmonary Hypertension in Patients With Chronic Obstructive Pulmonary Disease.

PURPOSE: To determine diagnostic validity of cardiopulmonary exercise testing (CPX) parameters for detecting pulmonary hypertension (PH) in patients with chronic obstructive pulmonary disease (COPD) and to investigate association between CPX parameters and indices of PH. METHODS: This cross-sectional study enrolled 48 moderate to very severe COPD patients in whom PH was confirmed by echocardiography. Symptom-limited CPX was performed using an incremental exercise protocol. Relevant CPX parameters were derived and were tested for their diagnostic ability for diagnosing PH. Logistic regression was applied to examine the effect of various clinical covariates on the diagnostic ability of exercise test variables for detecting PH. RESULTS: Of the 48 patients, 29 were diagnosed with PH and 19 were negative for PH based on echocardiographic testing. CPX measures including peak oxygen uptake (% predicted (Equation is included in full-text article.)O2peak, (Equation is included in full-text article.)O2peak [mL/min], (Equation is included in full-text article.)O2/kg), oxygen pulse ((Equation is included in full-text article.)O2/HR % predicted, (Equation is included in full-text article.)O2/HR mL/beat), and peak minute ventilation ((Equation is included in full-text article.)Epeak [L/m]) were inversely correlated with mean pulmonary arterial pressure (mPAP). Peak (Equation is included in full-text article.)O2/HR and (Equation is included in full-text article.)O2peak were found to be significant predictors of PH in univariate analysis. (Equation is included in full-text article.)O2peak (%), (Equation is included in full-text article.)O2/HR (mL/beat), and desaturation (%) were identified as independent predictors of PH adjusted for age, forced expiratory volume in 1 sec (%), and forced vital capacity (L). CONCLUSION: The present study validates the use of CPX parameters such as (Equation is included in full-text article.)O2peak and (Equation is included in full-text article.)O2/HR as a diagnostic tool for correctly identifying PH in COPD patients. Therefore, CPX may be used as an adjunct to echocardiographic measurement of PH where there is unavailability of equipment and expertise.

Electromyographic analysis of upper trapezius, abductor pollicis longus and abductor pollicis brevis during smartphone use in different positions among young male and female subjects.

BACKGROUND: Smartphone use has increased tremendously in recent times and there are various adverse musculoskeletal consequences associated with its use. Alteration in the activation patterns of muscles in certain positions may be the reason behind the development of musculoskeletal disorders in smartphone users; however, it has not been thoroughly investigated by the existing literature. OBJECTIVES: To investigate the electromyographic (EMG) activity of upper trapezius (UT), abductor pollicis brevis (APB) and abductor pollicis longus (APL) during smartphone use in three different positions (standing, sitting on the chair and sitting cross legged on the floor) in young male versus female subjects. METHODS: Twenty-six young male (age: 23.77 ± 2.47 years) and 26 young female (age: 22.45 ± 2.32 years) smartphone users were recruited from Centre for Physiotherapy and Rehabilitation Sciences, Jamia Millia Islamia, New Delhi, India. EMG activity of UT, APB and APL muscles was examined using surface electrodes during a smartphone task in three different positions, i.e. standing, sitting on a chair, sitting cross-legged on the floor. The smartphone task consisted of typing English quotations for 20 s 3 times with a rest period of 10 s between each quotation and a 5-min interval between each position, respectively. RESULTS: EMG activity of the UT muscle was found to be significantly reduced when sitting on a chair as compared to standing (p < 0.001) and sitting cross-legged (p = 0.008) during smartphone use. APB and APL muscle activity were not significantly different between the three positions (p > 0.05). Moreover, the activation patterns of these muscles did not differ in male and female subjects (p > 0.05). CONCLUSION: The present study demonstrates that the UT muscle is least activated when sitting on chair as compared to standing and sitting cross-legged during smartphone use. Moreover, the activity of neck and thumb muscles does not vary significantly between male and female subjects during smartphone use in different positions. As UT muscle activation significantly varies with the position of smartphone use, thus, the position adopted during smartphone use should be taken into consideration and the position which causes least strain on muscles, i.e. sitting on the chair should be adopted.

Diagnostic performance of resting and post-exercise heart rate variability for detecting cardiac autonomic neuropathy in type 2 diabetes mellitus.

BACKGROUND: Post-exercise recovery phase is associated with clustering of various cardiovascular events and, therefore, monitoring of cardiac autonomic control via heart rate variability (HRV) during this phase may allow identification of autonomic alterations that are not evident under resting conditions in type 2 diabetes mellitus (T2DM) patients. PURPOSE: To investigate and compare the diagnostic performance of resting and post-exercise HRV for detecting cardiac autonomic neuropathy (CAN) in T2DM patients. METHODS: Forty-two T2DM patients were categorized as CAN-positive and CAN-negative based on standard cardiovascular autonomic reflex tests (CARTs). Short-term resting and post-exercise HRV after a graded exercise test were evaluated for each participant. Diagnostic performance of both resting and post-exercise HRV measures was computed using standard statistical procedures. RESULTS: Diagnostic testing yielded superior diagnostic performance of post-exercise HRV than resting HRV measures. Root mean square of successive differences (RMSSD) between adjacent R-R intervals (p = 0.01), percentage of consecutive N-N intervals that vary by >50 ms (pNN50) (p = 0.03) and total power (TP) (p = 0.01) were significantly better diagnostic indicators of CAN under post-exercise conditions than at rest. Predictive ability of these post-exercise HRV measures for CAN was maintained after adjusting various clinical confounders to cardiac autonomic function. CONCLUSION: Post-exercise HRV measures such as TP, RMSSD and pNN50 were found to be more accurate diagnostic tests for detecting CAN than resting HRV. Hence, monitoring of the HRV measures proposed here during exercise testing protocols may provide important diagnostic information regarding CAN in T2DM.

Sleep duration is a significant predictor of cardiac autonomic neuropathy in type 2 diabetes mellitus.

AIM: To investigate the association between sleep quality outcomes and measures of cardiac autonomic function and to assess the predictive ability of sleep quality outcomes for cardiac autonomic neuropathy (CAN) in type 2 diabetes mellitus (T2DM). METHODS: Fifty patients with T2DM (age, 51.3±7.01years; glycemic control, 8.4±1.65%) completed the study. Patients were diagnosed for CAN using the standard clinical autonomic test battery and were also assessed for heart rate variability (HRV) under resting conditions. Sleep quality was examined using the Pittsburg Sleep Quality Index (PSQI). RESULTS: Sleep duration, sleep onset latency, sleep efficiency, daytime dysfunction and global PSQI score showed significant correlations with measures of cardiac autonomic control (p<0.05). At an optimal cut-off of≤5.83h (area under the curve: 0.76, p=0.0003; sensitivity: 50%; specificity: 94.4%), sleep duration predicted occurrence of CAN (odds ratio, confidence interval: 0.18, 0.04-0.70; p=0.01) in T2DM after adjusting for various clinical confounders. CONCLUSION: Findings of the present study suggest that subjective sleep outcomes such as sleep duration, sleep onset latency, sleep efficiency, daytime dysfunction and overall sleep quality are associated with the indices of cardiac autonomic function in T2DM. Moreover, short sleep duration may be considered a predictor in the occurrence of CAN in these patients. Considering the role of sleep in the pathophysiology of CAN, sleep should be routinely examined in patients with T2DM and appropriate therapeutic interventions should be implemented particularly in case of reduced sleep duration.

Subclinical inflammation and endothelial dysfunction are linked to cardiac autonomic neuropathy in type 2 diabetes.

PURPOSE: The present study aimed to examine association between inflammatory and endothelial function biomarkers and indices of cardiac autonomic control in T2DM patients. METHODS: 50 T2DM patients were recruited for this study. For cardiac autonomic function, cardiovascular autonomic reflex tests (CARTs) and heart rate variability (HRV) analysis was performed. Blood samples were collected for evaluating inflammatory and endothelial function biomarkers. Multivariable linear regression analysis adjusted for diabetes duration, glycemic control, waist circumference, hypertension, dyslipidemia, metformin, and statins was performed to examine the association between the biomarkers and cardiac autonomic function parameters. RESULTS: Interleukin-6 was inversely related to total power (p = .009) and low frequency power (p = .04). Interleukin-18 and high sensitivity C-reactive protein inversely correlated with measures of cardiac vagal control (p < .05). Both nitric oxide and endothelial nitric oxide synthase were positively linked with cardiac vagal control indices (p < .05) whereas endothelin-1 did not show any independent association with cardiac autonomic function parameters. CONCLUSIONS: Biomarkers of inflammation and endothelial function are associated with measures of cardiac vagal control and global HRV which suggest that there is some pathophysiological link between subclinical inflammation, endothelial dysfunction and cardiac autonomic dysfunction in T2DM.

Does resistance training modulate cardiac autonomic control? A systematic review and meta-analysis.

PURPOSE: To systematically evaluate the literature on the effects of resistance training (RT) on cardiac autonomic control in healthy and diseased individuals. METHODS: Electronic databases Pubmed, PEDro, and Scopus were systematically searched from their inception up to June 2018. Randomized controlled trials, quasi-experimental trials, and cross-over controlled trials investigating the effect of RT (of at least 4 weeks duration) on cardiac autonomic control assessed either by linear or non-linear measures of heart rate variability (HRV), baroreflex sensitivity, or post-exercise heart rate recovery were included. Of the studies retrieved, 28 were included in the systematic review. Meta-analysis was performed on 21 studies of the total 28 studies. RESULTS: Quality and characteristic assessment revealed fair quality evidence. The majority of literature on healthy humans suggested no change in cardiac autonomic control following RT. Standardized mean differences (SMD) showed a significant effect of RT on root mean square of successive differences between adjacent inter-beat (R-R) intervals (RMSSD) [SMD 0.96, 95% confidence interval (CI) 0.20-1.73; p = 0.01], ratio of low- to high-frequency power of HRV (LF/HF ratio; SMD -0.72, 95% CI -1.03 to -0.42; p < 0.00001), standard deviation of the instantaneous beat-to-beat variability (SD1; SMD 1.78, 95% CI 1.07-2.49, p < 0.00001), and sample entropy (SMD 1.17, 95% CI 0.36-1.97, p = 0.005) in diseased individuals. CONCLUSION: This rigorous systematic analysis revealed that RT has no or minimal effects on cardiac autonomic control of healthy individuals, but RT leads to improvement in cardiac autonomic control of diseased individuals.

Effects of selective strengthening of tibialis posterior and stretching of iliopsoas on navicular drop, dynamic balance, and lower limb muscle activity in pronated feet: A randomized clinical trial.

Objectives: Flexibility and strength are compromised in pronated feet, which could in turn lead to alteration of the dynamic balance and muscle activity in the lower extremities. This study aimed to analyze the effects of selective tibialis posterior strengthening and iliopsoas stretching on navicular drop, dynamic balance, and lower limb muscle activity in young adults with pronated feet. Methods: Twenty-eight participants with pronated feet were randomly assigned to either the stretching and strengthening group (n = 14) or the conventional exercise group (n = 14). The stretching and strengthening group performed tibialis posterior strengthening exercises and iliopsoas stretching three times a week for 6 weeks in addition to the conventional towel curl exercises. The conventional exercise group performed towel curl exercises only. Navicular drop, dynamic balance, and lower limb muscle activity were assessed at baseline and post-intervention. A mixed model analysis of variance was performed to test the study hypothesis. Results: Significant group effects for the activity of tibialis anterior (p = 0.003) and abductor hallucis muscle (p = 0.010), as well as for the posterolateral (p = 0.036) and composite reach scores (p = 0.018), were detected. Significant group × time interactions were observed for naviculardrop (p < 0.001), all dynamic balance components (p < 0.001), and the activity of tibialis anterior (p < 0.001) and abductor hallucis (p < 0.001). Conclusions: This study demonstrated that inclusion of selective tibialis posterior strengthening and iliopsoas stretching in addition to the conventional towel curl exercise program could improve important clinical outcomes, such as navicular drop, muscle activity, and dynamic balance in flatfeet.

Correlation Between Upper Body Balance, Muscle Strength, and Power in Cricketers Belonging to Different Age Groups.

OBJECTIVE: The purpose of this study was to assess correlation between variables of upper body balance, muscular strength, and power in cricketers belonging to different age groups. METHODS: Forty-eight healthy male cricketers (26 adolescents aged 14-17 years and 22 adults aged 18-25 years) were recruited from Jamia Millia Islamia, New Delhi, India. After a warm-up, the participants underwent Upper Quarter Y Balance Test, backward overhead medicine ball throw test, and back-strength testing in a random order. RESULTS: Values of the Pearson correlation coefficient for muscle strength and upper body power were found to be 0.397 and 0.499 for adolescent and adult cricketers, respectively. Correlation coefficient values for upper body balance and strength range from -0.008 to 0.05 and 0.325 to 0.414 and for upper body balance and power range from 0.059 to 0.062 and 0.133 to 0.153 for adolescent and adult cricketers, respectively. CONCLUSION: Statistically significant, moderate-sized correlations were demonstrated between muscular strength and upper body power in adolescent and adult cricketers. However, no correlations existed between upper body balance and power and upper body balance and muscular strength in these athletes.

Reliability of Electromyographic Assessment of Biceps Brachii and Triceps Brachii in Cricketers.

OBJECTIVE: The purpose of this study is to determine the intraexaminer and interexaminer reliability of electromyographic assessment of biceps brachii (BB) and triceps brachii (TB) muscles in cricketers. METHODS: Sixteen healthy male cricketers (ages 14-35 years) recruited from Jamia Millia Islamia, New Delhi, India were tested on 2 occasions that were held 1 week apart. On the first occasion, only examiner 1 performed the testing; on the second occasion, examiner 1, examiner 2, and examiner 3 all performed testing. While testing for surface electromyography (sEMG) activity of BB and TB muscles, participants were asked to produce maximal voluntary isometric contraction (MVIC), which was to be held for 5 seconds against the resistance provided by an examiner. Participants performed 3 MVICs per muscle per examiner, with a rest interval of 3 minutes between consecutive contractions. Intraclass correlation coefficient, standard error of measurement, and minimum detectable change were calculated to determine the reliability of repeated sEMG measurements. RESULTS: Nonsignificant differences were observed for the 2 trials completed by examiner 1 (paired t test) and testing done by all 3 examiners (repeated measures analysis of variance) at P < .05 for both BB and TB. Intraclass correlation coefficient values ranged from .84 to .86 for BB and .89 to .98 for TB. Standard error of measurement (minimum detectable change) was .052 (.144) mV and .041 (.114) mV for BB intraexaminer and interexaminer reliability testing, respectively, and .018 (.051) mV and .043 (.119) mV for TB intraexaminer and interexaminer reliability testing. Ninety-five percent of the mean differences between almost all of the repeated measurements were found to lie within the agreement intervals estimated by Bland-Altman plots. CONCLUSION: This preliminary study suggests that sEMG is a reliable tool with excellent intraexaminer and interexaminer reliability for assessing the activity of BB and TB muscles in male cricketers. These findings suggest that sEMG can be used to assess MVIC activity of these muscles in clinical settings, as well as in research area.