ABSTRACT
We describe a case of H1N1 pneumonia with left upper lobe bronchial atresia. Although bronchial atresia as an isolated occurrence is an innocuous finding, but when it is superimposed by another major insult, it can amplify the disease effect and can have adverse implications leading to significant morbidity. This report highlights the fact that anatomical anomalies can be the cause of inordinately severe or prolonged course of acute respiratory infection in children.
Subject(s)
Bronchi/diagnostic imaging , Influenza, Human/diagnostic imaging , Pneumonia, Viral/diagnostic imaging , Respiratory System Abnormalities/diagnostic imaging , Bronchi/abnormalities , Bronchoscopy , Child , Female , Humans , Influenza A Virus, H1N1 Subtype , Influenza, Human/complications , Influenza, Human/therapy , Pneumonia, Viral/complications , Pneumonia, Viral/therapy , Radiography, Thoracic , Respiratory System Abnormalities/complications , Respiratory System Abnormalities/diagnosis , Tomography, X-Ray ComputedSubject(s)
Acute Lung Injury/chemically induced , Bleomycin/adverse effects , Ethiodized Oil/adverse effects , Pneumonia, Lipid/chemically induced , Sclerotherapy/adverse effects , Bleomycin/administration & dosage , Child, Preschool , Contrast Media/adverse effects , Female , Humans , Sclerosing Solutions/administration & dosage , Sclerosing Solutions/adverse effects , Vascular Malformations/therapyABSTRACT
BACKGROUND: We conducted a sero-survey among pregnant women attending antenatal clinics of six hospitals which also function as sentinel sites for CRS surveillance, to estimate the prevalence of IgG antibodies against rubella. METHODS: We systematically sampled 1800 pregnant women attending antenatal clinics and tested their sera for IgG antibodies against rubella. We classified sera as seropositive (titre ≥10â¯IU/ml), sero-negative (titre <8â¯IU/ml) or indeterminate (titre 8-9.9â¯IU/ml) per manufacturer's instructions. In a sub-sample, we estimated the titers of IgG antibodies against rubella. IgG titer of ≥10â¯IU/mL was considered protective. RESULTS: Of 1800 sera tested, 1502 (83.4%) were seropositive and 24 (1.3%) were indeterminate and 274 (15.2%) were sero-negative. Rubella sero-positivity did not differ by age group, educational status or place of residence. Three hundred and eighty three (87.8%) of the 436 sera had IgG concentrations ≥10â¯IU/mL. CONCLUSION: The results of the serosurvey indicate high levels of rubella sero-positivity in pregnant women. High sero-prevalence in the absence of routine childhood immunization indicates continued transmission of rubella virus in cities where sentinel sites are located.
Subject(s)
Antibodies, Viral/blood , Pregnancy Complications, Infectious/epidemiology , Rubella/epidemiology , Adolescent , Adult , Cross-Sectional Studies , Female , Humans , Immunoglobulin G/blood , India/epidemiology , Pregnancy , Pregnant Women , Prevalence , Rubella virus , Sentinel Surveillance , Seroepidemiologic Studies , Tertiary Care Centers , Vaccination/statistics & numerical data , Young AdultABSTRACT
An infant aged 6 weeks presented with failure to thrive since birth, fever and lethargy for 4 days. The child was fed on unpasteurised diluted goat's milk after birth. She was diagnosed to have brucellosis both by blood culture and serology. Her mother's Brucella serology was negative. She was successfully treated with injection amikacin and tablet rifampicin and had satisfactory weight gain thereafter. Acquired brucellosis should be considered in the differential diagnosis of failure to thrive in young infants.
