A bi-directional deep learning architecture for lung nodule semantic segmentation.

Lung nodules are abnormal growths and lesions may exist. Both lungs may have nodules. Most lung nodules are harmless (not cancerous/malignant). Pulmonary nodules are rare in lung cancer. X-rays and CT scans identify the lung nodules. Doctors may term the growth a lung spot, coin lesion, or shadow. It is necessary to obtain properly computed tomography (CT) scans of the lungs to get an accurate diagnosis and a good estimate of the severity of lung cancer. This study aims to design and evaluate a deep learning (DL) algorithm for identifying pulmonary nodules (PNs) using the LUNA-16 dataset and examine the prevalence of PNs using DB-Net. The paper states that a new, resource-efficient deep learning architecture is called for, and it has been given the name of DB-NET. When a physician orders a CT scan, they need to employ an accurate and efficient lung nodule segmentation method because they need to detect lung cancer at an early stage. However, segmentation of lung nodules is a difficult task because of the nodules' characteristics on the CT image as well as the nodules' concealed shape, visual quality, and context. The DB-NET model architecture is presented as a resource-efficient deep learning solution for handling the challenge at hand in this paper. Furthermore, it incorporates the Mish nonlinearity function and the mask class weights to improve segmentation effectiveness. In addition to the LUNA-16 dataset, which contained 1200 lung nodules collected during the LUNA-16 test, the LUNA-16 dataset was extensively used to train and assess the proposed model. The DB-NET architecture surpasses the existing U-NET model by a dice coefficient index of 88.89%, and it also achieves a similar level of accuracy to that of human experts.

A Reliable Machine Intelligence Model for Accurate Identification of Cardiovascular Diseases Using Ensemble Techniques.

Machine intelligence can convert raw clinical data into an informational source that helps make decisions and predictions. As a result, cardiovascular diseases are more likely to be addressed as early as possible before affecting the lifespan. Artificial intelligence has taken research on disease diagnosis and identification to another level. Despite several methods and models coming into existence, there is a possibility of improving the classification or forecast accuracy. By selecting the connected combination of models and features, we can improve accuracy. To achieve a better solution, we have proposed a reliable ensemble model in this paper. The proposed model produced results of 96.75% on the cardiovascular disease dataset obtained from the Mendeley Data Center, 93.39% on the comprehensive dataset collected from IEEE DataPort, and 88.24% on data collected from the Cleveland dataset. With this proposed model, we can achieve the safety and health security of an individual.

Identifying the presence of bacteria on digital images by using asymmetric distribution with k-means clustering algorithm.

This paper is mainly aimed at the decomposition of image quality assessment study by using Three Parameter Logistic Mixture Model and k-means clustering (TPLMM-k). This method is mainly used for the analysis of various images which were related to several real time applications and for medical disease detection and diagnosis with the help of the digital images which were generated by digital microscopic camera. Several algorithms and distribution models had been developed and proposed for the segmentation of the images. Among several methods developed and proposed, the Gaussian Mixture Model (GMM) was one of the highly used models. One can say that almost the GMM was playing the key role in most of the image segmentation research works so far noticed in the literature. The main drawback with the distribution model was that this GMM model will be best fitted with a kind of data in the dataset. To overcome this problem, the TPLMM-k algorithm is proposed. The image decomposition process used in the proposed algorithm had been analyzed and its performance was analyzed with the help of various performance metrics like the Variance of Information (VOI), Global Consistency Error (GCE) and Probabilistic Rand Index (PRI). According to the results, it is shown that the proposed algorithm achieves the better performance when compared with the previous results of the previous techniques. In addition, the decomposition of the images had been improved in the proposed algorithm.

3D CNN with Visual Insights for Early Detection of Lung Cancer Using Gradient-Weighted Class Activation.

The 3D convolutional neural network is able to make use of the full nonlinear 3D context information of lung nodule detection from the DICOM (Digital Imaging and Communications in Medicine) images, and the Gradient Class Activation has shown to be useful for tailoring classification tasks and localization interpretation for fine-grained features and visual explanation for the internal working. Gradient-weighted class activation plays a crucial role for clinicians and radiologists in terms of trusting and adopting the model. Practitioners not only rely on a model that can provide high precision but also really want to gain the respect of radiologists. So, in this paper, we explored the lung nodule classification using the improvised 3D AlexNet with lightweight architecture. Our network employed the full nature of the multiview network strategy. We have conducted the binary classification (benign and malignant) on computed tomography (CT) images from the LUNA 16 database conglomerate and database image resource initiative. The results obtained are through the 10-fold cross-validation. Experimental results have shown that the proposed lightweight architecture achieved a superior classification accuracy of 97.17% on LUNA 16 dataset when compared with existing classification algorithms and low-dose CT scan images as well.

An effective method for computerized prediction and segmentation of multiple sclerosis lesions in brain MRI.

BACKGROUND AND OBJECTIVES: Multiple sclerosis is one of the major diseases and the progressive MS lesion formation often leads to cognitive decline and physical disability. A quick and perfect method for estimating the number and size of MS lesions in the brain is very important in estimating the progress of the disease and effectiveness of treatments. But, the accurate identification, characterization and quantification of MS lesions in brain magnetic resonance imaging (MRI) is extremely difficult due to the frequent change in location, size, morphology variation, intensity similarity with normal brain tissues, and inter-subject anatomical variation of brain images. METHODS: This paper presents a method where adaptive background generation and binarization using global threshold are the key steps for MS lesions detection and segmentation. After performing three phase level set, we add third phase segmented region with contour of brain to connect the normal tissues near the boundary. Then remove all lesions except maximum connected area and corpus callosum of the brain to generate adaptive background. The binarization method is used to select threshold based on entropy and standard deviation preceded by non-gamut image enhancement. The background image is then subtracted from binarized image to find out segmented MS lesions. RESULTS: The step of subtraction of background from binarized image does not generate spurious lesions. Binarization steps correctly identify the MS lesions and reduce over or under segmentation. The average Kappa index is 94.88%, Jacard index is 90.43%, correct detection ration is 92.60284%, false detection ratio is 2.55% and relative area error is 5.97% for proposed method. Existing recent methods does not have such accuracy and low value of error rate both mathematically as well as visually due to many spurious lesions generation and over segmentation problems. CONCLUSIONS: Proposed method accurately identifies the size and number of lesions as well as location of lesions detection as a radiologist performs. The adaptability of the proposed method creates a number of potential opportunities for use in clinical practice for the detection of MS lesions in MRI. Proposed method gives an improved accuracy and low error compare to existing recent methods.

Designing a bioengine for detection and analysis of base string on an affected sequence in high-concentration regions.

We design an Algorithm for bioengine. As a program are enable optimal alignments searching between two sequences, the host sequence (normal plant) as well as query sequence (virus). Searching for homologues has become a routine operation of biological sequences in 4 × 4 combination with different subsequence (word size). This program takes the advantage of the high degree of homology between such sequences to construct an alignment of the matching regions. There is a main aim which is to detect the overlapping reading frames. This program also enables to find out the highly infected colones selection highest matching region with minimum gap or mismatch zones and unique virus colones matches. This is a small, portable, interactive, front-end program intended to be used to find out the regions of matching between host sequence and query subsequences. All the operations are carried out in fraction of seconds, depending on the required task and on the sequence length.

Diagnosis of breast cancer by tissue analysis.

In this paper, we propose a technique to locate abnormal growth of cells in breast tissue and suggest further pathological test, when require. We compare normal breast tissue with malignant invasive breast tissue by a series of image processing steps. Normal ductal epithelial cells and ductal/lobular invasive carcinogenic cells also consider for comparison here in this paper. In fact, features of cancerous breast tissue (invasive) are extracted and analyses with normal breast tissue. We also suggest the breast cancer recognition technique through image processing and prevention by controlling p53 gene mutation to some extent.

A comparative study of wireless sensor networks and their routing protocols.

Recent developments in the area of micro-sensor devices have accelerated advances in the sensor networks field leading to many new protocols specifically designed for wireless sensor networks (WSNs). Wireless sensor networks with hundreds to thousands of sensor nodes can gather information from an unattended location and transmit the gathered data to a particular user, depending on the application. These sensor nodes have some constraints due to their limited energy, storage capacity and computing power. Data are routed from one node to other using different routing protocols. There are a number of routing protocols for wireless sensor networks. In this review article, we discuss the architecture of wireless sensor networks. Further, we categorize the routing protocols according to some key factors and summarize their mode of operation. Finally, we provide a comparative study on these various protocols.