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1.
Head Face Med ; 12(1): 26, 2016 Aug 02.
Article in English | MEDLINE | ID: mdl-27485368

ABSTRACT

BACKGROUND: To assess, analyze and compare the results of graft uptake using Tragal Cartilage-Perichondrium Composite (TCPC) graft with Temporalis Fascia (TF) graft in patients who undergoing surgery for chronic otitis media - squamous type. METHODS: Patients aged 13 years and above with diagnosis of chronic otitis media - squamous type undergoing modified radical mastoidectomy, either primary or revision surgery with grafting of tympanic membrane (TM) and patients undergoing excision of postero-superior retraction pocket (PSRP) were included in this study. Patients were divided in two groups: Group A-patients undergoing TCPC graft and Group B -patients undergoing TF graft. Graft uptake results were assessed between 8-12 weeks of surgery. RESULTS: In both Groups there were 30 patients each. In Group A successful graft uptake was seen in 27 patients (90 %) and failure of graft uptake was seen in 3 patients(10 %). In Group B successful graft uptake was seen in 28 patients (93.3 %) and failure in 2 patients (6.67 %).Out of the total 60 patients, 11 patients had PSRP. All 6 patients with PSRP in Group A had successful graft uptake and no retraction. Among the 5 patients with PSRP in Group B all patients had sucessful graft uptake, however, in 2 patients retraction of the tympanic membrane was seen similar to the preoperative findings. CONCLUSIONS: There was no statistical difference (p = 0.433) between the use of temporalis fascia or tragal cartilage perichondrium in patients undergoing surgery for chronic otitis media - squamous type.


Subject(s)
Cartilage/transplantation , Fascia/transplantation , Myringoplasty/methods , Otitis Media, Suppurative/pathology , Otitis Media, Suppurative/surgery , Adolescent , Chi-Square Distribution , Chronic Disease , Female , Follow-Up Studies , Graft Rejection , Graft Survival , Humans , Longitudinal Studies , Male , Otitis Media, Suppurative/diagnosis , Prospective Studies , Risk Assessment , Tissue Transplantation/methods , Tissue and Organ Harvesting/methods , Treatment Outcome , Tympanic Membrane Perforation/diagnosis , Tympanic Membrane Perforation/surgery , Young Adult
2.
JNMA J Nepal Med Assoc ; 47(172): 224-7, 2008.
Article in English | MEDLINE | ID: mdl-19079400

ABSTRACT

This study was done to compare the pre and post-operative hearing results in patients undergoing canal wall down mastoidectomy with classical type III tympanoplasty using temporalis fascia alone. Patients of >or=5 years age with the diagnosis of Chronic otitis media (squamous) with conductive or mixed hearing loss, needing canal wall down mastoidectomy and with intact and mobile stapes suprastructure at surgery who underwent classical type III tympanoplasty were included in the study. The pre and post-operative PTA was performed and evaluated. The post-operative hearing was assessed in terms of average ABG and size of ABG closure. Mean pre and post-operative air bone gap in classical type III tympanoplasty were 37.8 dB and 29.8 dB respectively and these differences were statistically significant. The postoperative PTA-ABG ranged from 15-61.2 dB. Hearing results after type III tympanoplasty varied widely showing statistically significant improvement in mean post-operative PTA-ABG but there was a great variation.


Subject(s)
Hearing Loss, Mixed Conductive-Sensorineural/physiopathology , Hearing/physiology , Mastoid/surgery , Otitis Media/surgery , Tympanoplasty/methods , Adolescent , Adult , Audiometry, Pure-Tone , Child , Child, Preschool , Female , Follow-Up Studies , Hearing Loss, Mixed Conductive-Sensorineural/etiology , Hearing Loss, Mixed Conductive-Sensorineural/surgery , Humans , Male , Otitis Media/complications , Otitis Media/physiopathology , Postoperative Period , Prospective Studies , Treatment Outcome , Young Adult
3.
Nepal Med Coll J ; 9(4): 284-5, 2007 Dec.
Article in English | MEDLINE | ID: mdl-18298023

ABSTRACT

This is a case report of myiasis in modified radical mastoidectomy cavity in a 48 years old male presented in the Department of ENT and Head and Neck Surgery, T.U. Teaching Hospital, Katmandu, Nepal. Around 50 maggots were removed from his mastoid cavity. Patient was managed with turpentine oil and antibiotics which was given to prevent secondary infection. Literature search revealed only one case report of Myiasis infestation in a postoperative mastoid cavity.


Subject(s)
Mastoid/surgery , Myiasis/diagnosis , Oils, Volatile/chemistry , Postoperative Complications , Animals , Humans , Male , Middle Aged , Myiasis/surgery , Myiasis/therapy , Nepal , Postoperative Period , Risk Factors , Time Factors , Turpentine
4.
J Asian Nat Prod Res ; 8(4): 309-15, 2006 Jun.
Article in English | MEDLINE | ID: mdl-16864441

ABSTRACT

Fats and phthalic acid derivatives were isolated and characterised based on their spectral analysis from the antifouling activity guided fractions of n-hexane and methanol extract of the brown alga Sargassum confusum. The fractions, as well as the isolated compounds, demonstrated significant antifouling activity against spores of a major fouling alga Ulva pertusa with 50-75% decrease of spore attachment on agar-coated slides.


Subject(s)
Lipids/chemistry , Lipids/pharmacology , Phthalic Acids/chemistry , Phthalic Acids/pharmacology , Sargassum/chemistry , Lipids/isolation & purification , Molecular Structure , Phthalic Acids/isolation & purification , Spores/drug effects , Ulva/drug effects
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