ABSTRACT
Neuromyelitis Optica (NMO), previously regarded as a form of multiple sclerosis, is defined by Gault and Devic, as a retrobulbar neuritis or papillitis accompanied by acute myelitis and occasionally other neurological symptom or signs not restricted to the spinal cord or optic nerves. With the diagnosis of specific antibodies, probable role of humoral immunity supports its pathogenesis. Only a few cases of NMO have been reported in association with pulmonary tuberculosis (TB). Here we report a case of young girl with acute onset paraplegia diagnosed to have NMO, who later on during hospital stay developed ascites which cultured positive for Mycobacterium tuberculosis. This association of abdominal TB with NMO is under-reported in literature.
Subject(s)
Antitubercular Agents/therapeutic use , Methylprednisolone/therapeutic use , Neuromyelitis Optica/diagnosis , Neuromyelitis Optica/drug therapy , Tuberculosis/complications , Tuberculosis/drug therapy , Evoked Potentials, Visual , Female , Humans , Magnetic Resonance Imaging , Mycobacterium tuberculosis/isolation & purification , Neuromyelitis Optica/etiology , Paraplegia/etiology , Spinal Cord/pathology , Treatment Outcome , Tuberculosis/diagnosis , Young AdultABSTRACT
Amyloidosis and multiple myeloma are included in the same spectrum of clonal plasma cell disorders. Amyloidosis can present with localized deposits or manifest as systemic disease involving multiple organs. Here we are reporting a case of an elderly female, having amyloidosis leading to facial disfigurement and neuropathy for many years and then presenting with concomitant multiple myeloma as an incidental diagnosis with no typical symptoms related to it at all.
